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TMTC2 transmembrane O-mannosyltransferase targeting cadherins 2 [ Bubalus bubalis (water buffalo) ]

Gene ID: 102412352, updated on 10-Mar-2024

Summary

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Gene symbol
TMTC2
Gene description
transmembrane O-mannosyltransferase targeting cadherins 2
See related
EnsemblRapid:ENSBALG00030018341
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs
human mouse all
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Genomic context

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See TMTC2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
14
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 4 NC_059160.1 (107376146..107793881, complement)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 4 NC_058346.1 (106122760..106540495, complement)

Chromosome 4 - NC_059160.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112584643 Neighboring gene uncharacterized LOC123333342 Neighboring gene small nucleolar RNA SNORA18 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC123333343 Neighboring gene uncharacterized LOC112584644 Neighboring gene uncharacterized LOC123333344 Neighboring gene uncharacterized LOC102413674 Neighboring gene methyltransferase like 25

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein O-linked mannosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein O-mannosyl-transferase TMTC2
Names
transmembrane and tetratricopeptide repeat containing 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059160.1 Reference NDDB_SH_1 Primary Assembly

    Range
    107376146..107793881 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025284384.2 → XP_025140169.1  protein O-mannosyl-transferase TMTC2 isoform X2

    Related
    ENSBALP00030034776.1, ENSBALT00030051769.1
    Conserved Domains (3) summary
    COG0457
    Location:481 → 712
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:527 → 555
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:248 → 321
    DUF1736; Domain of unknown function (DUF1736)

  2. XM_006054570.3 → XP_006054632.1  protein O-mannosyl-transferase TMTC2 isoform X4

    See identical proteins and their annotated locations for XP_006054632.1

    Related
    ENSBALP00030034764.1, ENSBALT00030051749.1
    Conserved Domains (7) summary
    sd00006
    Location:527 → 555
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:779 → 812
    TPR_1; Tetratricopeptide repeat
    pfam07719
    Location:609 → 638
    TPR_2; Tetratricopeptide repeat
    pfam08409
    Location:247 → 321
    DUF1736; Domain of unknown function (DUF1736)
    pfam13414
    Location:493 → 554
    TPR_11; TPR repeat
    pfam13424
    Location:557 → 634
    TPR_12; Tetratricopeptide repeat
    pfam14559
    Location:755 → 822
    TPR_19; Tetratricopeptide repeat

  3. XM_044941876.1 → XP_044797811.1  protein O-mannosyl-transferase TMTC2 isoform X3

    Conserved Domains (2) summary
    COG0457
    Location:364 → 605
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:410 → 438
    TPR; TPR repeat [structural motif]

  4. XM_044941874.1 → XP_044797809.1  protein O-mannosyl-transferase TMTC2 isoform X1

    Conserved Domains (2) summary
    COG0457
    Location:364 → 605
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:410 → 438
    TPR; TPR repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

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