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PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 [ Bubalus bubalis (water buffalo) ]

Gene ID: 102404618, updated on 10-Mar-2024

Summary

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Gene symbol
PIK3C3
Gene description
phosphatidylinositol 3-kinase catalytic subunit type 3
See related
EnsemblRapid:ENSBALG00030010740
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs
human mouse all
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Genomic context

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See PIK3C3 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
26
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 22 NC_059178.1 (48000267..48167293)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 22 NC_058364.1 (47826656..48011177)

Chromosome 22 - NC_059178.1Genomic Context describing neighboring genes Neighboring gene actin-related protein 6-like Neighboring gene uncharacterized LOC123331184 Neighboring gene 40S ribosomal protein S27-like Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene RWD domain-containing protein 1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in autophagosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in autophagy of peroxisome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in phagophore assembly site IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class III, type I IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class III, type II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3-kinase catalytic subunit type 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059178.1 Reference NDDB_SH_1 Primary Assembly

    Range
    48000267..48167293
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006056957.4 → XP_006057019.1  phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1

    See identical proteins and their annotated locations for XP_006057019.1

    Related
    ENSBALP00030020339.1, ENSBALT00030030051.1
    Conserved Domains (3) summary
    cd08397
    Location:26 → 186
    C2_PI3K_class_III; C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks)
    cd00870
    Location:283 → 503
    PI3Ka_III; Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III ...
    cd00896
    Location:539 → 883
    PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase

  2. XM_044934742.2 → XP_044790677.1  phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X3

    Related
    ENSBALP00030020438.1, ENSBALT00030030151.1
    Conserved Domains (3) summary
    cd08397
    Location:26 → 186
    C2_PI3K_class_III; C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks)
    cd00896
    Location:477 → 821
    PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase
    cl00271
    Location:283 → 441
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in ...

  3. XM_044934741.2 → XP_044790676.1  phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X2

    Related
    ENSBALP00030020408.1, ENSBALT00030030121.1
    Conserved Domains (3) summary
    cd08397
    Location:26 → 186
    C2_PI3K_class_III; C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks)
    cd00870
    Location:251 → 471
    PI3Ka_III; Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III ...
    cd00896
    Location:507 → 851
    PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase

  4. XM_025273515.2 → XP_025129300.1  phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X4

    Related
    ENSBALP00030020248.1, ENSBALT00030029960.1
    Conserved Domains (3) summary
    cd08397
    Location:26 → 186
    C2_PI3K_class_III; C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks)
    cd00870
    Location:283 → 503
    PI3Ka_III; Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III ...
    cd00896
    Location:539 → 748
    PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase
Nucleotide Protein
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