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PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [ Bubalus bubalis (water buffalo) ]

Gene ID: 102403911, updated on 10-Mar-2024

Summary

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Gene symbol
PFKFB3
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
See related
EnsemblRapid:ENSBALG00030013046
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
18
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 14 NC_059170.1 (72173896..72255673, complement)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 14 NC_058356.1 (71331008..71412764, complement)

Chromosome 14 - NC_059170.1Genomic Context describing neighboring genes Neighboring gene protein kinase C theta Neighboring gene uncharacterized LOC123464905 Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene RNA binding motif protein 17 Neighboring gene interleukin 2 receptor subunit alpha

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059170.1 Reference NDDB_SH_1 Primary Assembly

    Range
    72173896..72255673 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044928265.2 → XP_044784200.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X4

    Conserved Domains (1) summary
    PTZ00322
    Location:120 → 530
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

  2. XM_006044079.4 → XP_006044141.2  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X2

    Related
    ENSBALP00030024505.1, ENSBALT00030036542.1
    Conserved Domains (1) summary
    PTZ00322
    Location:120 → 534
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

  3. XM_044928264.2 → XP_044784199.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X3

    Conserved Domains (1) summary
    PTZ00322
    Location:120 → 534
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

  4. XM_006044077.4 → XP_006044139.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X6

    See identical proteins and their annotated locations for XP_006044139.1

    Related
    ENSBALP00030024473.1, ENSBALT00030036482.1
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:27 → 246
    6PF2K; 6-phosphofructo-2-kinase

  5. XM_044928263.2 → XP_044784198.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X1

    Conserved Domains (1) summary
    PTZ00322
    Location:120 → 534
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

  6. XM_044928266.2 → XP_044784201.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X5

    Related
    ENSBALP00030024446.1, ENSBALT00030036441.1
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 435
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:27 → 246
    6PF2K; 6-phosphofructo-2-kinase
Nucleotide Protein
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