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PKD2 polycystin 2, transient receptor potential cation channel [ Bubalus bubalis (water buffalo) ]

Gene ID: 102403362, updated on 10-Mar-2024

Summary

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Gene symbol
PKD2
Gene description
polycystin 2, transient receptor potential cation channel
See related
EnsemblRapid:ENSBALG00030031821
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs
human mouse all
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Genomic context

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See PKD2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
15
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 7 NC_059163.1 (80656859..80715548)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 7 NC_058349.1 (80832051..80890786)

Chromosome 7 - NC_059163.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102402718 Neighboring gene secreted phosphoprotein 1 Neighboring gene ATP binding cassette subfamily G member 2 (JR blood group) Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1K

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables muscle alpha-actinin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated sodium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of mechanical stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
polycystin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059163.1 Reference NDDB_SH_1 Primary Assembly

    Range
    80656859..80715548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044946061.2 → XP_044801996.2  polycystin-2 isoform X2

  2. XM_025290259.3 → XP_025146044.3  polycystin-2 isoform X1

    Related
    ENSBALP00030058307.1, ENSBALT00030087815.1
    Conserved Domains (4) summary
    cd15902
    Location:756 → 784
    EFh_HEF; EF-hand motif [structural motif]
    cl23634
    Location:726 → 794
    EFh_HEF; EF-hand, calcium binding motif, found in the hexa-EF hand proteins family
    pfam08016
    Location:271 → 689
    PKD_channel; Polycystin cation channel
    pfam18109
    Location:836 → 870
    Fer4_24; Ferredoxin I 4Fe-4S cluster domain
Nucleotide Protein
Heading Accession and Version

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