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LEPR leptin receptor [ Bubalus bubalis (water buffalo) ]

Gene ID: 102402159, updated on 10-Mar-2024

Summary

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Gene symbol
LEPR
Gene description
leptin receptor
See related
EnsemblRapid:ENSBALG00030018246
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Also known as
LPR; OB-R
Orthologs
human mouse all
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Genomic context

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See LEPR in Genome Data Viewer
Location:
chromosome: 6
Exon count:
21
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 6 NC_059162.1 (79414607..79507516, complement)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 6 NC_058348.1 (78704497..78797629, complement)

Chromosome 6 - NC_059162.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S3a-like Neighboring gene phosphodiesterase 4B Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene transfer RNA arginine (anticodon UCU)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evaluation of leptin receptor expression on buffalo leukocytes. De Matteis G, et al. Vet Immunol Immunopathol, 2016 Sep. PMID 27436440
  2. Characterization of leptin receptor gene in Bubalus bubalis and association analysis with body measurement traits. De Matteis G, et al. Mol Biol Rep, 2015 Jun. PMID 25431006
  3. Partial cloning and localization of leptin and leptin receptor in the mammary gland of the Egyptian water buffalo. Sayed-Ahmed A, et al. Domest Anim Endocrinol, 2003 Oct. PMID 14550514
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leptin receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059162.1 Reference NDDB_SH_1 Primary Assembly

    Range
    79414607..79507516 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044944888.2 → XP_044800823.1  leptin receptor isoform X2

    UniProtKB/TrEMBL
    A0A1D8F0M7
    Related
    ENSBALP00030034403.1, ENSBALT00030051186.1
    Conserved Domains (2) summary
    smart00060
    Location:741 → 820
    FN3; Fibronectin type 3 domain
    cd00063
    Location:237 → 330
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  2. XM_025288536.3 → XP_025144321.2  leptin receptor isoform X1

    Related
    ENSBALP00030034371.1, ENSBALT00030051133.1
    Conserved Domains (2) summary
    smart00060
    Location:741 → 820
    FN3; Fibronectin type 3 domain
    cd00063
    Location:237 → 330
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
Nucleotide Protein
Heading Accession and Version

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