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MCC MCC regulator of WNT signaling pathway [ Bubalus bubalis (water buffalo) ]

Gene ID: 102401931, updated on 10-Mar-2024

Summary

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Gene symbol
MCC
Gene description
MCC regulator of WNT signaling pathway
See related
EnsemblRapid:ENSBALG00030002778
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs
human mouse all
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Genomic context

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See MCC in Genome Data Viewer
Location:
chromosome: 11
Exon count:
20
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 11 NC_059167.1 (101678290..102202110, complement)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 11 NC_058353.1 (101086546..101608026, complement)

Chromosome 11 - NC_059167.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123328268 Neighboring gene uncharacterized LOC123328269 Neighboring gene receptor accessory protein 5 Neighboring gene U6 spliceosomal RNA Neighboring gene decapping mRNA 2 Neighboring gene uncharacterized LOC123328271 Neighboring gene uncharacterized LOC123328270 Neighboring gene transmembrane protein 126A-like Neighboring gene uncharacterized LOC102392951 Neighboring gene olfactory receptor 5W2-like Neighboring gene transfer RNA lysine (anticodon UUU)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De Novo Transcriptome Assembly of the Chinese Swamp Buffalo by RNA Sequencing and SSR Marker Discovery. Deng T, et al. PLoS One, 2016. PMID 26766209, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
colorectal mutant cancer protein
Names
MCC, WNT signaling pathway regulator
mutated in colorectal cancers

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059167.1 Reference NDDB_SH_1 Primary Assembly

    Range
    101678290..102202110 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025296457.3 → XP_025152242.2  colorectal mutant cancer protein isoform X1

    Related
    ENSBALP00030004898.1, ENSBALT00030007682.1

  2. XM_025296459.2 → XP_025152244.1  colorectal mutant cancer protein isoform X2

    Related
    ENSBALP00030004878.1, ENSBALT00030007652.1
    Conserved Domains (2) summary
    pfam10506
    Location:402 → 465
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
    cl25732
    Location:558 → 821
    SMC_N; RecF/RecN/SMC N terminal domain
Nucleotide Protein
Heading Accession and Version

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