INSIG2 insulin induced gene 2 [Bubalus bubalis (water buffalo)] - Gene

Summary

Gene symbol: INSIG2
Gene description: insulin induced gene 2
See related: EnsemblRapid:ENSBALG00030001262
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bubalus bubalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
103	current	NDDB_SH_1 (GCF_019923935.1)	2	NC_059158.1 (121983611..122028023)
102	previous assembly	NDDB_DH_1 (GCF_019923925.1)	2	NC_058344.1 (121271189..121315594)

Chromosome 2 - NC_059158.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

polymorphisms in buffalo INSIG2 gene are associated with milk production traits.
Title: Four novel polymorphisms of buffalo INSIG2 gene are associated with milk production traits in Chinese buffaloes.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in SREBP signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in SREBP-SCAP complex retention in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to insulin stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cholesterol biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of SREBP-SCAP-Insig complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: insulin-induced gene 2 protein

Names: insulin induced protein 2; insulin-induced 2 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.