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PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 [ Bubalus bubalis (water buffalo) ]

Gene ID: 102397767, updated on 10-Mar-2024

Summary

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Gene symbol
PFKFB2
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
See related
EnsemblRapid:ENSBALG00030001063
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs
human mouse all
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Genomic context

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See PFKFB2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
18
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 5 NC_059161.1 (76414288..76442907, complement)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 5 NC_058347.1 (75382961..75411580, complement)

Chromosome 5 - NC_059161.1Genomic Context describing neighboring genes Neighboring gene complement component 4 binding protein alpha Neighboring gene transfer RNA glutamic acid (anticodon CUC) Neighboring gene complement component 4 binding protein beta Neighboring gene YOD1 deubiquitinase Neighboring gene chromosome 5 C1orf116 homolog Neighboring gene uncharacterized LOC123333743

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De Novo Transcriptome Assembly of the Chinese Swamp Buffalo by RNA Sequencing and SSR Marker Discovery. Deng T, et al. PLoS One, 2016. PMID 26766209, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059161.1 Reference NDDB_SH_1 Primary Assembly

    Range
    76414288..76442907 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025277728.3 → XP_025133513.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform X1

    Conserved Domains (2) summary
    pfam00300
    Location:253 → 436
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:27 → 250
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_044943258.2 → XP_044799193.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform X1

    Conserved Domains (2) summary
    pfam00300
    Location:253 → 436
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:27 → 250
    6PF2K; 6-phosphofructo-2-kinase

  3. XM_025277726.3 → XP_025133511.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform X1

    Conserved Domains (2) summary
    pfam00300
    Location:253 → 436
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:27 → 250
    6PF2K; 6-phosphofructo-2-kinase

  4. XM_044943260.2 → XP_044799195.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform X1

    Conserved Domains (2) summary
    pfam00300
    Location:253 → 436
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:27 → 250
    6PF2K; 6-phosphofructo-2-kinase

  5. XM_025277730.3 → XP_025133515.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform X1

    Related
    ENSBALP00030001918.1, ENSBALT00030002888.1
    Conserved Domains (2) summary
    pfam00300
    Location:253 → 436
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:27 → 250
    6PF2K; 6-phosphofructo-2-kinase

  6. XM_044943259.2 → XP_044799194.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform X1

    Conserved Domains (2) summary
    pfam00300
    Location:253 → 436
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:27 → 250
    6PF2K; 6-phosphofructo-2-kinase

  7. XM_025277727.3 → XP_025133512.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform X1

    Related
    ENSBALP00030001949.1, ENSBALT00030002928.1
    Conserved Domains (2) summary
    pfam00300
    Location:253 → 436
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:27 → 250
    6PF2K; 6-phosphofructo-2-kinase

  8. XM_044943261.2 → XP_044799196.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform X3

    Related
    ENSBALP00030001970.1, ENSBALT00030002957.1
    Conserved Domains (2) summary
    pfam00300
    Location:253 → 436
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:27 → 250
    6PF2K; 6-phosphofructo-2-kinase

  9. XM_025277732.3 → XP_025133517.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform X2

    Related
    ENSBALP00030001978.1, ENSBALT00030002966.1
    Conserved Domains (2) summary
    pfam01591
    Location:27 → 250
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:253 → 436
    His_Phos_1; Histidine phosphatase superfamily (branch 1)

  10. XM_025277731.3 → XP_025133516.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform X1

    Conserved Domains (2) summary
    pfam00300
    Location:253 → 436
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:27 → 250
    6PF2K; 6-phosphofructo-2-kinase

  11. XM_044943262.2 → XP_044799197.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform X4

    Conserved Domains (1) summary
    COG0406
    Location:63 → 237
    PhoE; Broad specificity phosphatase PhoE [Carbohydrate transport and metabolism]
Nucleotide Protein
Heading Accession and Version

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