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PLCG2 phospholipase C gamma 2 [ Bubalus bubalis (water buffalo) ]

Gene ID: 102396307, updated on 10-Mar-2024

Summary

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Gene symbol
PLCG2
Gene description
phospholipase C gamma 2
See related
EnsemblRapid:ENSBALG00030038526
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs
human mouse all
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Genomic context

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See PLCG2 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
34
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 18 NC_059174.1 (7993372..8157921)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 18 NC_058360.1 (7935473..8093349)

Chromosome 18 - NC_059174.1Genomic Context describing neighboring genes Neighboring gene c-Maf inducing protein Neighboring gene uncharacterized LOC102396823 Neighboring gene uncharacterized LOC123330232 Neighboring gene nucleolar protein 8-like Neighboring gene small nucleolar RNA SNORA70 Neighboring gene short chain dehydrogenase/reductase family 42E, member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of epithelial cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059174.1 Reference NDDB_SH_1 Primary Assembly

    Range
    7993372..8157921
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044931908.2 → XP_044787843.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

    Related
    ENSBALP00030071110.1, ENSBALT00030106552.1
    Conserved Domains (10) summary
    cd00275
    Location:1212 → 1338
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:462 → 609
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:792 → 895
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:678 → 778
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11969
    Location:924 → 978
    SH3_PLCgamma2; Src homology 3 domain of Phospholipase C (PLC) gamma 2
    cd13234
    Location:991 → 1060
    PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
    cd13362
    Location:173 → 291
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    cd16215
    Location:296 → 449
    EFh_PI-PLCgamma2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
    cl14615
    Location:1077 → 1182
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
    cl17171
    Location:626 → 661
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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