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C1R complement C1r [ Bubalus bubalis (water buffalo) ]

Gene ID: 102395781, updated on 10-Mar-2024

Summary

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Gene symbol
C1R
Gene description
complement C1r
See related
EnsemblRapid:ENSBALG00030026949
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs
human all
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Genomic context

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See C1R in Genome Data Viewer
Location:
chromosome: 4
Exon count:
13
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 4 NC_059160.1 (16548422..16559851, complement)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 4 NC_058346.1 (16343033..16372091, complement)

Chromosome 4 - NC_059160.1Genomic Context describing neighboring genes Neighboring gene complement C1s Neighboring gene 40S ribosomal protein S28-like Neighboring gene NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial-like Neighboring gene complement C1r subcomponent-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De Novo Transcriptome Assembly of the Chinese Swamp Buffalo by RNA Sequencing and SSR Marker Discovery. Deng T, et al. PLoS One, 2016. PMID 26766209, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in blood microparticle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
complement C1r subcomponent

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059160.1 Reference NDDB_SH_1 Primary Assembly

    Range
    16548422..16559851 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025283127.3 → XP_025138912.1  complement C1r subcomponent isoform X2

    Related
    ENSBALP00030050696.1, ENSBALT00030075350.1
    Conserved Domains (5) summary
    smart00020
    Location:463 → 697
    Tryp_SPc; Trypsin-like serine protease
    smart00042
    Location:27 → 138
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    pfam00431
    Location:193 → 302
    CUB; CUB domain
    pfam00084
    Location:309 → 371
    Sushi; Sushi repeat (SCR repeat)
    pfam14670
    Location:161 → 189
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_025283126.3 → XP_025138911.1  complement C1r subcomponent isoform X2

    Related
    ENSBALP00030050684.1, ENSBALT00030075328.1
    Conserved Domains (5) summary
    smart00020
    Location:463 → 697
    Tryp_SPc; Trypsin-like serine protease
    smart00042
    Location:27 → 138
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    pfam00431
    Location:193 → 302
    CUB; CUB domain
    pfam00084
    Location:309 → 371
    Sushi; Sushi repeat (SCR repeat)
    pfam14670
    Location:161 → 189
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  3. XM_025283125.3 → XP_025138910.1  complement C1r subcomponent isoform X1

    Related
    ENSBALP00030050671.1, ENSBALT00030075304.1
    Conserved Domains (5) summary
    smart00020
    Location:471 → 705
    Tryp_SPc; Trypsin-like serine protease
    smart00042
    Location:35 → 146
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    pfam00431
    Location:201 → 310
    CUB; CUB domain
    pfam00084
    Location:317 → 379
    Sushi; Sushi repeat (SCR repeat)
    pfam14670
    Location:169 → 197
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
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