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ALOX12 arachidonate 12-lipoxygenase, 12S type [ Bubalus bubalis (water buffalo) ]

Gene ID: 102395651, updated on 10-Mar-2024

Summary

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Gene symbol
ALOX12
Gene description
arachidonate 12-lipoxygenase, 12S type
See related
EnsemblRapid:ENSBALG00030006477
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs
human mouse all
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Genomic context

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See ALOX12 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
14
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 3 NC_059159.1 (36309337..36322262, complement)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 3 NC_058345.1 (36255976..36268901, complement)

Chromosome 3 - NC_059159.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102398273 Neighboring gene BPTF associated chromatin complex component 1 Neighboring gene ribonuclease K Neighboring gene transcription initiation factor TFIID subunit 13-like Neighboring gene CUE domain-containing protein 2-like Neighboring gene polyunsaturated fatty acid (12S)/(13S)-lipoxygenase, epidermal-type

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 12(S)-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables arachidonate 15-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables linoleate 13S-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
polyunsaturated fatty acid lipoxygenase ALOX12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059159.1 Reference NDDB_SH_1 Primary Assembly

    Range
    36309337..36322262 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006060101.3 → XP_006060163.1  polyunsaturated fatty acid lipoxygenase ALOX12 isoform X1

    Related
    ENSBALP00030012022.1, ENSBALT00030018058.1
    Conserved Domains (2) summary
    cd01753
    Location:2 → 111
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:217 → 654
    Lipoxygenase; Lipoxygenase

  2. XM_006060103.3 → XP_006060165.1  polyunsaturated fatty acid lipoxygenase ALOX12 isoform X2

    Conserved Domains (2) summary
    cd01753
    Location:2 → 111
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:217 → 547
    Lipoxygenase; Lipoxygenase
Nucleotide Protein
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