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ACLY ATP citrate lyase [ Alligator sinensis (Chinese alligator) ]

Gene ID: 102386616, updated on 10-Mar-2024

Summary

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Gene symbol
ACLY
Gene description
ATP citrate lyase
Gene type
protein coding
RefSeq status
MODEL
Organism
Alligator sinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae; Alligator
Orthologs
human mouse all
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Genomic context

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See ACLY in Genome Data Viewer
Location:
chromosome: Un
Exon count:
33
Annotation release Status Assembly Chr Location
102 current ASM45574v1 (GCF_000455745.1) Unplaced Scaffold NW_005842585.1 (460948..524089)

NW_005842585.1Genomic Context describing neighboring genes Neighboring gene 2',3'-cyclic nucleotide 3' phosphodiesterase Neighboring gene outer dynein arm docking complex subunit 4 Neighboring gene 7-methylguanosine phosphate-specific 5'-nucleotidase Neighboring gene kelch like family member 10 Neighboring gene FKBP prolyl isomerase 10

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005842585 Unplaced Scaffold Reference ASM45574v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP citrate synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in citrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP-citrate synthase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Alligator sinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM45574v1 Primary Assembly

Genomic

  1. NW_005842585.1 Reference ASM45574v1 Primary Assembly

    Range
    460948..524089
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006032765.3 → XP_006032827.1  ATP-citrate synthase isoform X1

    See identical proteins and their annotated locations for XP_006032827.1

    UniProtKB/TrEMBL
    A0A1U7SLU7
    Conserved Domains (2) summary
    cl25712
    Location:1 → 419
    SucC; Succinyl-CoA synthetase, beta subunit [Energy production and conversion]
    cl26126
    Location:491 → 1094
    Ligase_CoA; CoA-ligase

  2. XM_025214506.1 → XP_025070291.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1U7SLU7
    Conserved Domains (2) summary
    cl25712
    Location:1 → 419
    SucC; Succinyl-CoA synthetase, beta subunit [Energy production and conversion]
    cl26126
    Location:491 → 1094
    Ligase_CoA; CoA-ligase

  3. XM_025214505.1 → XP_025070290.1  ATP-citrate synthase isoform X1

    UniProtKB/TrEMBL
    A0A1U7SLU7
    Conserved Domains (2) summary
    cl25712
    Location:1 → 419
    SucC; Succinyl-CoA synthetase, beta subunit [Energy production and conversion]
    cl26126
    Location:491 → 1094
    Ligase_CoA; CoA-ligase

  4. XM_006032768.3 → XP_006032830.1  ATP-citrate synthase isoform X1

    See identical proteins and their annotated locations for XP_006032830.1

    UniProtKB/TrEMBL
    A0A1U7SLU7
    Conserved Domains (2) summary
    cl25712
    Location:1 → 419
    SucC; Succinyl-CoA synthetase, beta subunit [Energy production and conversion]
    cl26126
    Location:491 → 1094
    Ligase_CoA; CoA-ligase

  5. XM_014524256.2 → XP_014379742.1  ATP-citrate synthase isoform X2

    UniProtKB/TrEMBL
    A0A1U8DET8
    Conserved Domains (7) summary
    cd06100
    Location:846 → 1083
    CCL_ACL-C; Citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CCL cleaves citryl-CoA (CiCoA) to acetyl-CoA (AcCoA) and oxaloacetate (OAA). ...
    PLN02235
    Location:1 → 419
    PLN02235; ATP citrate (pro-S)-lyase
    PLN02522
    Location:481 → 1084
    PLN02522; ATP citrate (pro-S)-lyase
    pfam16114
    Location:247 → 421
    Citrate_bind; ATP citrate lyase citrate-binding
    cl17255
    Location:55 → 207
    ATP-grasp_4; ATP-grasp domain
    cl21454
    Location:487 → 590
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    cl22543
    Location:650 → 775
    Ligase_CoA; CoA-ligase
Nucleotide Protein
Heading Accession and Version

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