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HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 [ Alligator sinensis (Chinese alligator) ]

Gene ID: 102383729, updated on 10-Mar-2024

Summary

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Gene symbol
HMGCS2
Gene description
3-hydroxy-3-methylglutaryl-CoA synthase 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Alligator sinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae; Alligator
Orthologs
human mouse all
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Genomic context

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See HMGCS2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
102 current ASM45574v1 (GCF_000455745.1) Unplaced Scaffold NW_005842541.1 (41934..65780)

NW_005842541.1Genomic Context describing neighboring genes Neighboring gene regenerating family member 4 Neighboring gene phosphoglycerate dehydrogenase Neighboring gene myomegalin-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005842541 Unplaced Scaffold Reference ASM45574v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Alligator sinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM45574v1 Primary Assembly

Genomic

  1. NW_005842541.1 Reference ASM45574v1 Primary Assembly

    Range
    41934..65780
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025213609.1 → XP_025069394.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A3Q0HBH1
    Conserved Domains (1) summary
    cl27874
    Location:53 → 453
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal

  2. XM_006031940.3 → XP_006032002.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A1U7SHK8
    Conserved Domains (3) summary
    TIGR01833
    Location:53 → 510
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    pfam08540
    Location:227 → 510
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal
    cl09938
    Location:56 → 226
    cond_enzymes; Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the ...
Nucleotide Protein
Heading Accession and Version

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