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PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [ Alligator sinensis (Chinese alligator) ]

Gene ID: 102372482, updated on 10-Mar-2024

Summary

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Gene symbol
PIK3CB
Gene description
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Gene type
protein coding
RefSeq status
MODEL
Organism
Alligator sinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae; Alligator
Orthologs
human mouse all
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Genomic context

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See PIK3CB in Genome Data Viewer
Location:
chromosome: Un
Exon count:
36
Annotation release Status Assembly Chr Location
102 current ASM45574v1 (GCF_000455745.1) Unplaced Scaffold NW_005842288.1 (299506..481114)

NW_005842288.1Genomic Context describing neighboring genes Neighboring gene probable ATP-dependent RNA helicase DDX47 pseudogene Neighboring gene uncharacterized LOC112551000 Neighboring gene uncharacterized LOC112551006 Neighboring gene vesicle-associated membrane protein 2-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005842288 Unplaced Scaffold Reference ASM45574v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Alligator sinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM45574v1 Primary Assembly

Genomic

  1. NW_005842288.1 Reference ASM45574v1 Primary Assembly

    Range
    299506..481114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025209421.1 → XP_025065206.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2

    UniProtKB/TrEMBL
    A0A3Q0GZM5
    Conserved Domains (5) summary
    cd08693
    Location:323 → 498
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:535 → 700
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:704 → 1065
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  2. XM_025209412.1 → XP_025065197.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  3. XM_006028076.3 → XP_006028138.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  4. XM_025209409.1 → XP_025065194.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  5. XM_025209404.1 → XP_025065189.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  6. XM_025209407.1 → XP_025065192.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  7. XM_025209411.1 → XP_025065196.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  8. XM_025209398.1 → XP_025065183.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  9. XM_025209413.1 → XP_025065198.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  10. XM_025209416.1 → XP_025065201.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  11. XM_025209408.1 → XP_025065193.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  12. XM_025209406.1 → XP_025065191.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  13. XM_025209405.1 → XP_025065190.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  14. XM_025209402.1 → XP_025065187.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  15. XM_025209418.1 → XP_025065203.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  16. XM_025209417.1 → XP_025065202.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  17. XM_025209403.1 → XP_025065188.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  18. XM_025209419.1 → XP_025065204.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  19. XM_025209415.1 → XP_025065200.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  20. XM_025209401.1 → XP_025065186.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  21. XM_025209414.1 → XP_025065199.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

  22. XM_025209400.1 → XP_025065185.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1

    UniProtKB/TrEMBL
    A0A1U8D8B0
    Conserved Domains (5) summary
    cd08693
    Location:324 → 499
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:536 → 701
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:705 → 1066
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain

RNA

  1. XR_003095105.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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