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MASP2 MBL associated serine protease 2 [ Alligator sinensis (Chinese alligator) ]

Gene ID: 102370755, updated on 10-Mar-2024

Summary

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Gene symbol
MASP2
Gene description
MBL associated serine protease 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Alligator sinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae; Alligator
Orthologs
human mouse all
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Genomic context

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See MASP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
102 current ASM45574v1 (GCF_000455745.1) Unplaced Scaffold NW_005841851.1 (1218863..1238220, complement)

NW_005841851.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112551264 Neighboring gene castor zinc finger 1 Neighboring gene uncharacterized LOC112551263 Neighboring gene TAR DNA binding protein Neighboring gene somatostatin-2-like Neighboring gene spermidine synthase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005841851 Unplaced Scaffold Reference ASM45574v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mannan-binding lectin serine protease 2
Names
mannan binding lectin serine peptidase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Alligator sinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM45574v1 Primary Assembly

Genomic

  1. NW_005841851.1 Reference ASM45574v1 Primary Assembly

    Range
    1218863..1238220 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006016158.3 → XP_006016220.1  mannan-binding lectin serine protease 2 isoform X1

    UniProtKB/TrEMBL
    A0A1U7RDS4
    Conserved Domains (7) summary
    cd00033
    Location:297 → 359
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00020
    Location:442 → 681
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:24 → 133
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:443 → 684
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:363 → 428
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:186 → 290
    CUB; CUB domain
    pfam14670
    Location:149 → 177
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_014523151.2 → XP_014378637.1  mannan-binding lectin serine protease 2 isoform X2

    UniProtKB/TrEMBL
    A0A1U8DBL7
    Conserved Domains (2) summary
    cd00041
    Location:24 → 133
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam14670
    Location:149 → 177
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

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