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ASAH2 N-acylsphingosine amidohydrolase 2 [ Latimeria chalumnae (coelacanth) ]

Gene ID: 102355598, updated on 26-Apr-2024

Summary

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Gene symbol
ASAH2
Gene description
N-acylsphingosine amidohydrolase 2
See related
Ensembl:ENSLACG00000008976
Gene type
protein coding
RefSeq status
MODEL
Organism
Latimeria chalumnae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Coelacanthiformes; Coelacanthidae; Latimeria
Also known as
ASAH2B
Orthologs
human zebrafish all
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Genomic context

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See ASAH2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_04 current fLatCha1.pri (GCF_037176945.1) 8 NC_088146.1 (106924918..106991159, complement)
101 previous assembly LatCha1 (GCF_000225785.1) Unplaced Scaffold NW_005820230.1 (383908..448557, complement)

Chromosome 8 - NC_088146.1Genomic Context describing neighboring genes Neighboring gene protein kinase cGMP-dependent 1b Neighboring gene 5S ribosomal RNA Neighboring gene apobec1 complementation factor Neighboring gene sphingomyelin synthase 1b Neighboring gene multiple inositol-polyphosphate phosphatase 1b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables N-acylsphingosine amidohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in long-chain fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neutral ceramidase
Names
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037176945.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fLatCha1.pri

Genomic

  1. NC_088146.1 Reference fLatCha1.pri

    Range
    106924918..106991159 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006005598.3 → XP_006005660.1  neutral ceramidase

    UniProtKB/TrEMBL
    H3AKL3
    Related
    ENSLACP00000010184.1
    Conserved Domains (3) summary
    PTZ00487
    Location:26 → 732
    PTZ00487; ceramidase; Provisional
    pfam04734
    Location:58 → 566
    Ceramidase_alk; Neutral/alkaline non-lysosomal ceramidase, N-terminal
    pfam17048
    Location:568 → 732
    Ceramidse_alk_C; Neutral/alkaline non-lysosomal ceramidase, C-terminal
Nucleotide Protein
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