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HEXB hexosaminidase B (beta polypeptide) [ Latimeria chalumnae (coelacanth) ]

Gene ID: 102348190, updated on 2-May-2024

Summary

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Gene symbol
HEXB
Gene description
hexosaminidase B (beta polypeptide)
See related
Ensembl:ENSLACG00000005909
Gene type
protein coding
RefSeq status
MODEL
Organism
Latimeria chalumnae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Coelacanthiformes; Coelacanthidae; Latimeria
Orthologs
human zebrafish all
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Genomic context

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See HEXB in Genome Data Viewer
Location:
chromosome: 1
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_04 current fLatCha1.pri (GCF_037176945.1) 1 NC_088139.1 (150300091..150347891)
101 previous assembly LatCha1 (GCF_000225785.1) Unplaced Scaffold NW_005821015.1 (193453..241474, complement)

Chromosome 1 - NC_088139.1Genomic Context describing neighboring genes Neighboring gene ectodermal-neural cortex 1 Neighboring gene E3 SUMO-protein ligase ZBED1-like Neighboring gene GTP dependent ribosome recycling factor mitochondrial 2 Neighboring gene NSA2 ribosome biogenesis homolog (S. cerevisiae)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables beta-N-acetylhexosaminidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ganglioside catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycosaminoglycan metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-hexosaminidase subunit beta
Names
hexosaminidase subunit beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037176945.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fLatCha1.pri

Genomic

  1. NC_088139.1 Reference fLatCha1.pri

    Range
    150300091..150347891
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006009317.3 → XP_006009379.1  beta-hexosaminidase subunit beta isoform X1

    Conserved Domains (2) summary
    cd06562
    Location:193 → 536
    GH20_HexA_HexB-like; Beta-N-acetylhexosaminidases catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides. The hexA and hexB genes encode the ...
    pfam14845
    Location:47 → 171
    Glycohydro_20b2; beta-acetyl hexosaminidase like

  2. XM_006009318.3 → XP_006009380.1  beta-hexosaminidase subunit beta isoform X2

    UniProtKB/TrEMBL
    H3AAJ1
    Related
    ENSLACP00000006662.2
    Conserved Domains (2) summary
    cd06562
    Location:193 → 534
    GH20_HexA_HexB-like; Beta-N-acetylhexosaminidases catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides. The hexA and hexB genes encode the ...
    pfam14845
    Location:47 → 171
    Glycohydro_20b2; beta-acetyl hexosaminidase like
Nucleotide Protein
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