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EDEM3 ER degradation enhancer, mannosidase alpha-like 3 [ Latimeria chalumnae (coelacanth) ]

Gene ID: 102347632, updated on 29-Apr-2024

Summary

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Gene symbol
EDEM3
Gene description
ER degradation enhancer, mannosidase alpha-like 3
See related
Ensembl:ENSLACG00000002887
Gene type
protein coding
RefSeq status
MODEL
Organism
Latimeria chalumnae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Coelacanthiformes; Coelacanthidae; Latimeria
Orthologs
human zebrafish all
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Genomic context

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See EDEM3 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_04 current fLatCha1.pri (GCF_037176945.1) 6 NC_088144.1 (44950841..45037974, complement)
101 previous assembly LatCha1 (GCF_000225785.1) Unplaced Scaffold NW_005819383.1 (42544..149440, complement)

Chromosome 6 - NC_088144.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102354773 Neighboring gene uncharacterized protein C1orf21 Neighboring gene niban apoptosis regulator 1a Neighboring gene ring finger protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endoplasmic reticulum mannose trimming IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mannose trimming involved in glycoprotein ERAD pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ER degradation-enhancing alpha-mannosidase-like protein 3
Names
ER degradation enhancing alpha-mannosidase like protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037176945.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fLatCha1.pri

Genomic

  1. NC_088144.1 Reference fLatCha1.pri

    Range
    44950841..45037974 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005997268.3 → XP_005997330.1  ER degradation-enhancing alpha-mannosidase-like protein 3

    See identical proteins and their annotated locations for XP_005997330.1

    UniProtKB/TrEMBL
    H3A0Q9, M3XIW3
    Related
    ENSLACP00000003230.1
    Conserved Domains (2) summary
    cd02126
    Location:659 → 785
    PA_EDEM3_like; PA_EDEM3_like: protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar ...
    pfam01532
    Location:54 → 493
    Glyco_hydro_47; Glycosyl hydrolase family 47
Nucleotide Protein
Heading Accession and Version

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