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THBS3 thrombospondin 3 [ Bos mutus (wild yak) ]

Gene ID: 102271065, updated on 10-Mar-2024

Summary

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Gene symbol
THBS3
Gene description
thrombospondin 3
Locus tag
M91_20868
See related
Ensembl:ENSBMUG00000012603
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos mutus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See THBS3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
101 current BosGru_v2.0 (GCF_000298355.1) Unplaced Scaffold NW_005394029.1 (837560..847893, complement)

NW_005394029.1Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 46 Neighboring gene mucin 1, cell surface associated Neighboring gene metaxin 1 Neighboring gene glucosylceramidase beta 1 Neighboring gene endosomal transmembrane epsin interactor 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005394029.1 Unplaced Scaffold Reference BosGru_v2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The yak genome and adaptation to life at high altitude. Qiu Q, et al. Nat Genet, 2012 Jul 1. PMID 22751099
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heparin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
thrombospondin-3
Names
Thrombospondin-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos mutus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BosGru_v2.0 Primary Assembly

Genomic

  1. NW_005394029.1 Reference BosGru_v2.0 Primary Assembly

    Range
    837560..847893 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005898682.2 → XP_005898744.1  thrombospondin-3 isoform X2

    UniProtKB/TrEMBL
    A0A6B0S1W0
    Related
    ENSBMUP00000016650.1, ENSBMUT00000019266.1
    Conserved Domains (9) summary
    cd00054
    Location:307 → 343
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:519 → 541
    TSP3; TSP3 repeat_short [structural motif]
    sd00002
    Location:542 → 577
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:448 → 482
    TSP3_1C; TSP3 repeat_1C [structural motif]
    pfam02412
    Location:543 → 577
    TSP_3; Thrombospondin type 3 repeat
    pfam05735
    Location:732 → 929
    TSP_C; Thrombospondin C-terminal region
    pfam12947
    Location:369 → 398
    EGF_3; EGF domain
    cd16079
    Location:218 → 260
    TSP-3cc; Coiled coil region of thrombospondin-3 (TSP-3)
    cl22861
    Location:23 → 193
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

  2. XM_005898681.1 → XP_005898743.1  thrombospondin-3 isoform X1

    See identical proteins and their annotated locations for XP_005898743.1

    UniProtKB/TrEMBL
    A0A6B0S1W0, L8ICS4
    Related
    ENSBMUP00000016634.1, ENSBMUT00000019245.1
    Conserved Domains (9) summary
    cd00054
    Location:316 → 352
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:528 → 550
    TSP3; TSP3 repeat_short [structural motif]
    sd00002
    Location:551 → 586
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:457 → 491
    TSP3_1C; TSP3 repeat_1C [structural motif]
    pfam02412
    Location:552 → 586
    TSP_3; Thrombospondin type 3 repeat
    pfam05735
    Location:741 → 938
    TSP_C; Thrombospondin C-terminal region
    pfam12947
    Location:378 → 407
    EGF_3; EGF domain
    cd16079
    Location:227 → 269
    TSP-3cc; Coiled coil region of thrombospondin-3 (TSP-3)
    cl22861
    Location:23 → 193
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

  3. XM_005898683.2 → XP_005898745.1  thrombospondin-3 isoform X3

    UniProtKB/TrEMBL
    A0A6B0S1W0
    Related
    ENSBMUP00000016653.1, ENSBMUT00000019269.1
    Conserved Domains (9) summary
    cd00054
    Location:196 → 232
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    sd00001
    Location:408 → 430
    TSP3; TSP3 repeat_short [structural motif]
    sd00002
    Location:431 → 466
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:337 → 371
    TSP3_1C; TSP3 repeat_1C [structural motif]
    pfam02412
    Location:432 → 466
    TSP_3; Thrombospondin type 3 repeat
    pfam05735
    Location:621 → 818
    TSP_C; Thrombospondin C-terminal region
    pfam12947
    Location:258 → 287
    EGF_3; EGF domain
    cd16079
    Location:107 → 149
    TSP-3cc; Coiled coil region of thrombospondin-3 (TSP-3)
    cl22861
    Location:23 → 118
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
Nucleotide Protein
Heading Accession and Version

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