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dis3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease [ Xiphophorus maculatus (southern platyfish) ]

Gene ID: 102228078, updated on 10-Mar-2024

Summary

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Gene symbol
dis3
Gene description
DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
See related
Ensembl:ENSXMAG00000018215
Gene type
protein coding
RefSeq status
MODEL
Organism
Xiphophorus maculatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Xiphophorus
Orthologs
human zebrafish all
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Genomic context

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See dis3 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
21
Annotation release Status Assembly Chr Location
102 current X_maculatus-5.0-male (GCF_002775205.1) 22 NC_036464.1 (18360826..18370526)
101 previous assembly Xiphophorus_maculatus-4.4.2 (GCF_000241075.1) Unplaced Scaffold NW_005372606.1 (142581..151711, complement)

Chromosome 22 - NC_036464.1Genomic Context describing neighboring genes Neighboring gene Krueppel-like factor 5 Neighboring gene progesterone immunomodulatory binding factor 1 Neighboring gene bora aurora kinase A activator Neighboring gene mitotic spindle organizing protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-5'-RNA exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in rRNA catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of cytoplasmic exosome (RNase complex) IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of nuclear exosome (RNase complex) IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
exosome complex exonuclease RRP44
Names
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xiphophorus maculatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference X_maculatus-5.0-male Primary Assembly

Genomic

  1. NC_036464.1 Reference X_maculatus-5.0-male Primary Assembly

    Range
    18360826..18370526
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023327984.1 → XP_023183752.1  exosome complex exonuclease RRP44 isoform X2

    UniProtKB/TrEMBL
    M4AUW9
    Related
    ENSXMAP00000018264.2, ENSXMAT00000018291.2
    Conserved Domains (2) summary
    cd09862
    Location:9 → 195
    PIN_Rrp44; PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs
    COG0557
    Location:188 → 921
    VacB; Exoribonuclease R [Transcription]

  2. XM_005812165.3 → XP_005812222.1  exosome complex exonuclease RRP44 isoform X1

    UniProtKB/TrEMBL
    A0A3B5RBZ5, M4AUW9
    Related
    ENSXMAP00000041318.1, ENSXMAT00000025984.1
    Conserved Domains (3) summary
    cd09862
    Location:9 → 195
    PIN_Rrp44; PIN domain of yeast exosome subunit Rrp44 endoribonuclease and other eukaryotic homologs
    COG0557
    Location:188 → 922
    VacB; Exoribonuclease R [Transcription]
    pfam00773
    Location:465 → 793
    RNB; RNB domain
Nucleotide Protein Strain
Heading Accession and Version

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