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SQLE squalene epoxidase [ Capra hircus (goat) ]

Gene ID: 102187506, updated on 10-Mar-2024

Summary

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Gene symbol
SQLE
Gene description
squalene epoxidase
See related
EnsemblRapid:ENSCHIG00000025130
Gene type
protein coding
RefSeq status
MODEL
Organism
Capra hircus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
Orthologs
human mouse all
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Genomic context

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See SQLE in Genome Data Viewer
Location:
chromosome: 14
Exon count:
11
Annotation release Status Assembly Chr Location
102 current ASM170441v1 (GCF_001704415.1) 14 NC_030821.1 (66867014..66889586)
101 previous assembly CHIR_1.0 (GCF_000317765.1) 14 NC_022306.1 (25595202..25617948, complement)

Chromosome 14 - NC_030821.1Genomic Context describing neighboring genes Neighboring gene liprin-alpha-1 pseudogene Neighboring gene zinc finger protein 572 Neighboring gene WASH complex subunit 5 Neighboring gene NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase Neighboring gene uncharacterized LOC106502835

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables squalene monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
squalene monooxygenase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Capra hircus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM170441v1 Primary Assembly

Genomic

  1. NC_030821.1 Reference ASM170441v1 Primary Assembly

    Range
    66867014..66889586
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005688851.3 → XP_005688908.1  squalene monooxygenase

    See identical proteins and their annotated locations for XP_005688908.1

    UniProtKB/TrEMBL
    A0A452G1Z7, A0A8C2PI56
    Related
    ENSCHIP00000030356.1, ENSCHIT00000038228.2
    Conserved Domains (2) summary
    COG0644
    Location:124 → 419
    FixC; Dehydrogenase (flavoprotein) [Energy production and conversion]
    cl21454
    Location:275 → 546
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
Heading Accession and Version

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