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FGF21 fibroblast growth factor 21 [ Capra hircus (goat) ]

Gene ID: 102185860, updated on 10-Mar-2024

Summary

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Gene symbol
FGF21
Gene description
fibroblast growth factor 21
See related
EnsemblRapid:ENSCHIG00000025254
Gene type
protein coding
RefSeq status
MODEL
Organism
Capra hircus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
Orthologs
human mouse all
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Genomic context

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See FGF21 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
3
Annotation release Status Assembly Chr Location
102 current ASM170441v1 (GCF_001704415.1) 18 NC_030825.1 (56403257..56405520)
101 previous assembly CHIR_1.0 (GCF_000317765.1) 18 NC_022310.1 (53813867..53815791)

Chromosome 18 - NC_030825.1Genomic Context describing neighboring genes Neighboring gene izumo sperm-oocyte fusion 1 Neighboring gene fucosyltransferase 1 (H blood group) Neighboring gene branched chain amino acid transaminase 2 Neighboring gene uncharacterized LOC106503135 Neighboring gene hydroxysteroid 17-beta dehydrogenase 14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. MiR-26b-5p regulates the preadipocyte differentiation by targeting FGF21 in goats. Ma J, et al. In Vitro Cell Dev Biol Anim, 2021 Mar. PMID 33511524
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MiR-26b-5p regulates the preadipocyte differentiation by targeting FGF21 in goats.
    Title: MiR-26b-5p regulates the preadipocyte differentiation by targeting FGF21 in goats.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables fibroblast growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in animal organ morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibroblast growth factor 21

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Capra hircus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM170441v1 Primary Assembly

Genomic

  1. NC_030825.1 Reference ASM170441v1 Primary Assembly

    Range
    56403257..56405520
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005692688.3 → XP_005692745.1  fibroblast growth factor 21

    See identical proteins and their annotated locations for XP_005692745.1

    UniProtKB/TrEMBL
    A0A0U2UQ40
    Related
    ENSCHIP00000030527.1, ENSCHIT00000038399.2
    Conserved Domains (1) summary
    cl00060
    Location:47 → 164
    FGF; Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate ...
Nucleotide Protein
Heading Accession and Version

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