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HMGCL 3-hydroxy-3-methylglutaryl-CoA lyase [ Capra hircus (goat) ]

Gene ID: 102180980, updated on 11-Apr-2024

Summary

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Gene symbol
HMGCL
Gene description
3-hydroxy-3-methylglutaryl-CoA lyase
See related
EnsemblRapid:ENSCHIG00000026977
Gene type
protein coding
RefSeq status
MODEL
Organism
Capra hircus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
Orthologs
human mouse all
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Genomic context

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See HMGCL in Genome Data Viewer
Location:
chromosome: 2
Exon count:
9
Annotation release Status Assembly Chr Location
102 current ASM170441v1 (GCF_001704415.1) 2 NC_030809.1 (6836125..6855444, complement)
101 previous assembly CHIR_1.0 (GCF_000317765.1) 2 NC_022294.1 (128286062..128305557)

Chromosome 2 - NC_030809.1Genomic Context describing neighboring genes Neighboring gene lysophospholipase 2 Neighboring gene UDP-galactose-4-epimerase Neighboring gene alpha-L-fucosidase 1 Neighboring gene cannabinoid receptor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-leucine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ketone body biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA lyase, mitochondrial
Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Capra hircus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM170441v1 Primary Assembly

Genomic

  1. NC_030809.1 Reference ASM170441v1 Primary Assembly

    Range
    6836125..6855444 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005676858.2 → XP_005676915.1  hydroxymethylglutaryl-CoA lyase, mitochondrial

    UniProtKB/TrEMBL
    A0A452GAC9, A0A8C2SJ63
    Related
    ENSCHIP00000033396.1, ENSCHIT00000041274.1
    Conserved Domains (2) summary
    PLN02746
    Location:17 → 325
    PLN02746; hydroxymethylglutaryl-CoA lyase
    pfam00682
    Location:32 → 306
    HMGL-like; HMGL-like
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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