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MMP25 matrix metallopeptidase 25 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 102144147, updated on 12-Jun-2024

Summary

Gene symbol
MMP25
Gene description
matrix metallopeptidase 25
See related
Ensembl:ENSMFAG00000008798
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See MMP25 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 20 NC_088394.1 (3851094..3865445)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 20 NC_052274.1 (3081218..3095681)

Chromosome 20 - NC_088394.1Genomic Context describing neighboring genes Neighboring gene THO complex subunit 6 Neighboring gene BICD family like cargo adaptor 2 Neighboring gene putative uncharacterized protein FLJ46214 Neighboring gene guanine nucleotide exchange factor subunit RIC1 Neighboring gene zinc finger and SCAN domain containing 10 Neighboring gene uncharacterized LOC102115874 Neighboring gene zinc finger protein 205

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in collagen catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
matrix metalloproteinase-25

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088394.1 Reference T2T-MFA8v1.0

    Range
    3851094..3865445
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005591033.4XP_005591090.2  matrix metalloproteinase-25 isoform X1

  2. XM_015442612.3XP_015298098.1  matrix metalloproteinase-25 isoform X4

    Conserved Domains (4) summary
    cd00094
    Location:251444
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:51216
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam00413
    Location:51216
    Peptidase_M10; Matrixin
    pfam01471
    Location:121
    PG_binding_1; Putative peptidoglycan binding domain
  3. XM_065536967.1XP_065393039.1  matrix metalloproteinase-25 isoform X2

  4. XM_045382427.2XP_045238362.1  matrix metalloproteinase-25 isoform X3