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PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 102143726, updated on 10-Oct-2024

Summary

Gene symbol
PRKAA2
Gene description
protein kinase AMP-activated catalytic subunit alpha 2
See related
Ensembl:ENSMFAG00000031683
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See PRKAA2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 1 NC_088375.1 (177965871..178033873, complement)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 1 NC_052255.1 (166273830..166341355, complement)

Chromosome 1 - NC_088375.1Genomic Context describing neighboring genes Neighboring gene complement C8 alpha chain Neighboring gene FYN binding protein 2 Neighboring gene uncharacterized LOC135965376 Neighboring gene phospholipid phosphatase 3 Neighboring gene uncharacterized LOC107127367

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables AMP-activated protein kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
5'-AMP-activated protein kinase catalytic subunit alpha-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088375.1 Reference T2T-MFA8v1.0

    Range
    177965871..178033873 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045370295.2XP_045226230.1  5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A2K5UX98
    Conserved Domains (3) summary
    cd12200
    Location:395550
    AMPKA2_C; C-terminal regulatory domain of 5'-AMP-activated serine/threonine kinase, subunit alpha
    cd14404
    Location:285349
    UBA_AID_AAPK2; UBA-like autoinhibitory domain (AID) found in vertebrate 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPKalpha-2)
    cd14079
    Location:13268
    STKc_AMPK_alpha; Catalytic domain of the Alpha subunit of the Serine/Threonine Kinase, AMP-activated protein kinase
  2. XM_065521867.1XP_065377939.1  5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X3

  3. XM_045370304.2XP_045226239.1  5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X2

    Conserved Domains (3) summary
    cd14404
    Location:285349
    UBA_AID_AAPK2; UBA-like autoinhibitory domain (AID) found in vertebrate 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPKalpha-2)
    cd14079
    Location:13268
    STKc_AMPK_alpha; Catalytic domain of the Alpha subunit of the Serine/Threonine Kinase, AMP-activated protein kinase
    cl17070
    Location:395473
    AMPKA_C_like; C-terminal regulatory domain of 5'-AMP-activated protein kinase (AMPK) alpha subunit and similar domains