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PTGES2 prostaglandin E synthase 2 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 102140040, updated on 7-Jun-2024

Summary

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Gene symbol
PTGES2
Gene description
prostaglandin E synthase 2
See related
Ensembl:ENSMFAG00000035442
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
PGES2; mPGES-2
Orthologs
human mouse all
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Genomic context

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See PTGES2 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 15 NC_088389.1 (15860028..15867584)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 15 NC_052269.1 (99475187..99483481, complement)

Chromosome 15 - NC_088389.1Genomic Context describing neighboring genes Neighboring gene lipocalin 2 Neighboring gene U7 small nuclear RNA Neighboring gene uncharacterized LOC123569028 Neighboring gene solute carrier family 25 member 25

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure and possible catalytic mechanism of microsomal prostaglandin E synthase type 2 (mPGES-2). Yamada T, et al. J Mol Biol, 2005 May 20. PMID 15854652
  2. PGH2 degradation pathway catalyzed by GSH-heme complex bound microsomal prostaglandin E2 synthase type 2: the first example of a dual-function enzyme. Yamada T, et al. Biochemistry, 2007 Jul 17. PMID 17585783
  3. Microsomal prostaglandin E synthase-1 (mPGES-1) is the primary form of PGES expressed by the primate periovulatory follicle. Duffy DM, et al. Hum Reprod, 2005 Jun. PMID 15774546
  4. Identification and characterization of a novel type of membrane-associated prostaglandin E synthase. Tanikawa N, et al. Biochem Biophys Res Commun, 2002 Mar 8. PMID 11866447
  5. Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs. Osada N, et al. Mol Biol Evol, 2005 Oct. PMID 15944441

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables prostaglandin-E synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prostaglandin E synthase 2
Names
Microsomal prostaglandin E synthase 2
membrane-associated prostaglandin E synthase-2
microsomal prostaglandin E synthase-2
XP_045228642.2
XP_065386105.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088389.1 Reference T2T-MFA8v1.0

    Range
    15860028..15867584
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045372707.2 → XP_045228642.2  prostaglandin E synthase 2 isoform X1

  2. XM_065530033.1 → XP_065386105.1  prostaglandin E synthase 2 isoform X2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001284110.1: Suppressed sequence

    Description
    NM_001284110.1: This RefSeq record was removed as a result of standard genome annotation processing. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9N0A4.1 GenPept UniProtKB/Swiss-Prot:Q9N0A4

Gene LinkOut

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