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RAP1B RAP1B, member of RAS oncogene family [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 102133022, updated on 1-Aug-2024

Summary

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Gene symbol
RAP1B
Gene description
RAP1B, member of RAS oncogene family
See related
Ensembl:ENSMFAG00000046085
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 11 NC_088385.1 (75370196..75420746)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 11 NC_052265.1 (65381207..65431994)

Chromosome 11 - NC_088385.1Genomic Context describing neighboring genes Neighboring gene Mdm1 nuclear protein Neighboring gene 26S proteasome regulatory subunit 10B-like Neighboring gene small nucleolar RNA SNORA70 Neighboring gene keratin, type II cytoskeletal 8-like Neighboring gene nucleoporin 107 Neighboring gene solute carrier family 35 member E3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs. Osada N, et al. Mol Biol Evol, 2005 Oct. PMID 15944441
  2. Rate of evolution in brain-expressed genes in humans and other primates. Wang HY, et al. PLoS Biol, 2007 Feb. PMID 17194215, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GDP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Rap protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to cAMP IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of synaptic vesicle exocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras-related protein Rap-1b
Names
Ras-related protein Rap-1b
XP_005571546.1
XP_005571549.1
XP_005571550.1
XP_045221513.1
XP_045221514.1
XP_045221515.1
XP_045221516.1
XP_045221517.1
XP_045221518.1
XP_045221519.1
XP_045221520.1
XP_045221522.1
XP_045221523.1
XP_065380616.1
XP_065380617.1
XP_065380618.1
XP_065380619.1
XP_065380620.1
XP_065380621.1
XP_065380622.1
XP_065380623.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088385.1 Reference T2T-MFA8v1.0

    Range
    75370196..75420746
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045365582.2 → XP_045221517.1  ras-related protein Rap-1b isoform X1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  2. XM_045365584.2 → XP_045221519.1  ras-related protein Rap-1b isoform X1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  3. XM_045365581.2 → XP_045221516.1  ras-related protein Rap-1b isoform X1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  4. XM_065524546.1 → XP_065380618.1  ras-related protein Rap-1b isoform X1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2

  5. XM_065524547.1 → XP_065380619.1  ras-related protein Rap-1b isoform X1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2

  6. XM_045365578.2 → XP_045221513.1  ras-related protein Rap-1b isoform X1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  7. XM_005571493.4 → XP_005571550.1  ras-related protein Rap-1b isoform X2

    See identical proteins and their annotated locations for XP_005571550.1

    UniProtKB/TrEMBL
    A0A2K5WRV7, A0A805RHR9
    Related
    ENSMFAP00000039876.1
    Conserved Domains (1) summary
    cl38936
    Location:3 → 125
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  8. XM_045365580.2 → XP_045221515.1  ras-related protein Rap-1b isoform X1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  9. XM_045365583.2 → XP_045221518.1  ras-related protein Rap-1b isoform X1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  10. XM_065524551.1 → XP_065380623.1  ras-related protein Rap-1b isoform X2

    UniProtKB/TrEMBL
    A0A2K5WRV7, A0A805RHR9

  11. XM_045365579.2 → XP_045221514.1  ras-related protein Rap-1b isoform X1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  12. XM_045365587.2 → XP_045221522.1  ras-related protein Rap-1b isoform X2

    UniProtKB/TrEMBL
    A0A2K5WRV7, A0A805RHR9
    Conserved Domains (1) summary
    cl38936
    Location:3 → 125
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  13. XM_065524545.1 → XP_065380617.1  ras-related protein Rap-1b isoform X1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2

  14. XM_065524549.1 → XP_065380621.1  ras-related protein Rap-1b isoform X2

    UniProtKB/TrEMBL
    A0A2K5WRV7, A0A805RHR9

  15. XM_065524544.1 → XP_065380616.1  ras-related protein Rap-1b isoform X1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2

  16. XM_065524550.1 → XP_065380622.1  ras-related protein Rap-1b isoform X2

    UniProtKB/TrEMBL
    A0A2K5WRV7, A0A805RHR9

  17. XM_005571489.4 → XP_005571546.1  ras-related protein Rap-1b isoform X1

    See identical proteins and their annotated locations for XP_005571546.1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  18. XM_005571492.4 → XP_005571549.1  ras-related protein Rap-1b isoform X2

    See identical proteins and their annotated locations for XP_005571549.1

    UniProtKB/TrEMBL
    A0A2K5WRV7, A0A805RHR9
    Conserved Domains (1) summary
    cl38936
    Location:3 → 125
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  19. XM_065524548.1 → XP_065380620.1  ras-related protein Rap-1b isoform X1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2

  20. XM_045365585.2 → XP_045221520.1  ras-related protein Rap-1b isoform X1

    UniProtKB/Swiss-Prot
    Q4R9D4
    UniProtKB/TrEMBL
    G7PHZ9, Q25DA2
    Conserved Domains (1) summary
    cd04175
    Location:3 → 167
    Rap1; Rap1 family GTPase consists of Rap1a and Rap1b isoforms

  21. XM_045365588.2 → XP_045221523.1  ras-related protein Rap-1b isoform X2

    UniProtKB/TrEMBL
    A0A2K5WRV7, A0A805RHR9
    Conserved Domains (1) summary
    cl38936
    Location:3 → 125
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001285405.1: Suppressed sequence

    Description
    NM_001285405.1: This RefSeq record was removed as a result of standard genome annotation processing. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4R9D4.1 GenPept UniProtKB/Swiss-Prot:Q4R9D4

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