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SRD5A1 steroid 5 alpha-reductase 1 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 102126671, updated on 12-Jun-2024

Summary

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Gene symbol
SRD5A1
Gene description
steroid 5 alpha-reductase 1
See related
Ensembl:ENSMFAG00000002749
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
S5AR 1
Orthologs
human mouse all
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Genomic context

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See SRD5A1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 6 NC_088380.1 (6962265..6999525)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 6 NC_052260.1 (6447615..6485407)

Chromosome 6 - NC_088380.1Genomic Context describing neighboring genes Neighboring gene ubiquitin conjugating enzyme E2 QL1 Neighboring gene NOP2/Sun RNA methyltransferase 2 Neighboring gene uncharacterized LOC123573918 Neighboring gene terminal nucleotidyltransferase 4A Neighboring gene uncharacterized LOC135971232

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning, expression and functional characterization of type 1 and type 2 steroid 5 alpha-reductases from Cynomolgus monkey: comparisons with human and rat isoenzymes. Levy MA, et al. J Steroid Biochem Mol Biol, 1995 Apr. PMID 7734398
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in steroid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Names
SR type 1
Steroid 5-alpha-reductase 1
steroid 5 alpha-reductase type 1 isoenzyme
XP_005556631.2
XP_045249462.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088380.1 Reference T2T-MFA8v1.0

    Range
    6962265..6999525
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045393527.2 → XP_045249462.2  3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform X1

  2. XM_005556574.4 → XP_005556631.2  3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform X2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001287298.1: Suppressed sequence

    Description
    NM_001287298.1: This RefSeq record was removed as a result of standard genome annotation processing. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q28891.1 GenPept UniProtKB/Swiss-Prot:Q28891

Gene LinkOut

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