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GAD1 glutamate decarboxylase 1 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 102117015, updated on 1-Aug-2024

Summary

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Gene symbol
GAD1
Gene description
glutamate decarboxylase 1
See related
Ensembl:ENSMFAG00000045590
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See GAD1 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 12 NC_088386.1 (66396739..66443111)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 12 NC_052266.1 (55670907..55717299)

Chromosome 12 - NC_088386.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102116247 Neighboring gene glutamate rich 2 Neighboring gene uncharacterized LOC135966548 Neighboring gene golgi reassembly stacking protein 2 Neighboring gene tousled like kinase 1 Neighboring gene small nucleolar RNA U13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glutamate decarboxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in gamma-aminobutyric acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in presynaptic active zone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glutamate decarboxylase 1
Names
glutamate decarboxylase 1 (brain, 67kDa)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088386.1 Reference T2T-MFA8v1.0

    Range
    66396739..66443111
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005573441.4 → XP_005573498.1  glutamate decarboxylase 1 isoform X1

    See identical proteins and their annotated locations for XP_005573498.1

    UniProtKB/TrEMBL
    A0A2K5VV10, G7PKT2
    Related
    ENSMFAP00000028555.1
    Conserved Domains (1) summary
    pfam00282
    Location:144 → 518
    Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain

  2. XM_005573442.4 → XP_005573499.1  glutamate decarboxylase 1 isoform X2

    See identical proteins and their annotated locations for XP_005573499.1

    UniProtKB/TrEMBL
    A0A2K5VUQ6
    Related
    ENSMFAP00000028574.1
    Conserved Domains (1) summary
    cl18945
    Location:144 → 213
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

  3. XM_065525641.1 → XP_065381713.1  glutamate decarboxylase 1 isoform X2

    UniProtKB/TrEMBL
    A0A2K5VUQ6
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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