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PRKRA protein activator of interferon induced protein kinase EIF2AK2 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 102116511, updated on 1-Aug-2024

Summary

Gene symbol
PRKRA
Gene description
protein activator of interferon induced protein kinase EIF2AK2
See related
Ensembl:ENSMFAG00000040213
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See PRKRA in Genome Data Viewer
Location:
chromosome: 12
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 12 NC_088386.1 (74004360..74024977, complement)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 12 NC_052266.1 (63272712..63293420, complement)

Chromosome 12 - NC_088386.1Genomic Context describing neighboring genes Neighboring gene U5 spliceosomal RNA Neighboring gene oxysterol binding protein like 6 Neighboring gene U6 spliceosomal RNA Neighboring gene pejvakin Neighboring gene nuclear migration protein nudC-like Neighboring gene FKBP prolyl isomerase 7

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables siRNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of regulatory ncRNA processing IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in siRNA processing IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of RISC complex IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of RISC-loading complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
interferon-inducible double-stranded RNA-dependent protein kinase activator A
Names
protein kinase, interferon-inducible double stranded RNA dependent activator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088386.1 Reference T2T-MFA8v1.0

    Range
    74004360..74024977 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005573599.4XP_005573656.1  interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1

    See identical proteins and their annotated locations for XP_005573656.1

    UniProtKB/TrEMBL
    G7PIE7
    Related
    ENSMFAP00000035394.1
    Conserved Domains (3) summary
    cd19889
    Location:32102
    DSRM_PRKRA_rpt1; first double-stranded RNA binding motif of protein activator of the interferon-induced protein kinase (PRKRA) and similar proteins
    cd19891
    Location:126192
    DSRM_PRKRA_rpt2; second double-stranded RNA binding motif of protein activator of the interferon-induced protein kinase (PRKRA) and similar proteins
    cd19892
    Location:239310
    DSRM_PRKRA_rpt3; third double-stranded RNA binding motif of protein activator of the interferon-induced protein kinase (PRKRA) and similar proteins
  2. XM_045367323.2XP_045223258.1  interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X2

    UniProtKB/TrEMBL
    A0A2K5WED7
    Conserved Domains (2) summary
    cd19891
    Location:1379
    DSRM_PRKRA_rpt2; second double-stranded RNA binding motif of protein activator of the interferon-induced protein kinase (PRKRA) and similar proteins
    cd19892
    Location:126197
    DSRM_PRKRA_rpt3; third double-stranded RNA binding motif of protein activator of the interferon-induced protein kinase (PRKRA) and similar proteins
  3. XM_065526521.1XP_065382593.1  interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X2

    UniProtKB/TrEMBL
    A0A2K5WED7
  4. XM_015432416.3XP_015287902.1  interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X2

    UniProtKB/TrEMBL
    A0A2K5WED7
    Conserved Domains (2) summary
    cd19891
    Location:1379
    DSRM_PRKRA_rpt2; second double-stranded RNA binding motif of protein activator of the interferon-induced protein kinase (PRKRA) and similar proteins
    cd19892
    Location:126197
    DSRM_PRKRA_rpt3; third double-stranded RNA binding motif of protein activator of the interferon-induced protein kinase (PRKRA) and similar proteins