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UBE2R2-AS1 UBE2R2 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 101929688, updated on 10-Oct-2023

Summary

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Official Symbol
UBE2R2-AS1provided by HGNC
Official Full Name
UBE2R2 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:49911
See related
Ensembl:ENSG00000235481 AllianceGenome:HGNC:49911
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LINC01251
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Genomic context

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Location:
9p13.3
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (33724085..33818868, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (33742642..33837455, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (33724083..33818866, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene T cell receptor beta variable 26/OR9-2 (pseudogene) Neighboring gene uncharacterized LOC124902143 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28300 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:33721507-33722008 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:33722009-33722508 Neighboring gene MPRA-validated peak7221 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28301 Neighboring gene serine protease 3 Neighboring gene T cell receptor beta variable 29/OR9-2 (non-functional) Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:33796108-33796608 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28302 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19835 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19836 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19837 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19838 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19839 Neighboring gene ubiquitin conjugating enzyme E2 R2 Neighboring gene RNA, U4atac small nuclear 11, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28303 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:33927431-33928421 Neighboring gene small nucleolar RNA, C/D box 121B Neighboring gene ubiquitin associated protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. UBE2R2-AS1 Inhibits Xenograft Growth in Nude Mice and Correlates with a Positive Prognosis in Glioma. Xu W, et al. J Mol Neurosci, 2021 Aug. PMID 33528791
  2. Long noncoding RNA UBE2R2-AS1 promotes glioma cell apoptosis via targeting the miR-877-3p/TLR4 axis. Xu W, et al. Onco Targets Ther, 2019. PMID 31123407, Free PMC Article
  3. LncUBE2R2-AS1 acts as a microRNA sponge of miR-302b to promote HCC progression via activation EGFR-PI3K-AKT signaling pathway. Wu Z, et al. Cell Cycle, 2020 Oct. PMID 32835579, Free PMC Article
  4. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Ferreira MA, et al. Nat Genet, 2008 Sep. PMID 18711365, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. UBE2R2-AS1 Inhibits Xenograft Growth in Nude Mice and Correlates with a Positive Prognosis in Glioma.
    Title: UBE2R2-AS1 Inhibits Xenograft Growth in Nude Mice and Correlates with a Positive Prognosis in Glioma.
  2. LncUBE2R2-AS1 acts as a microRNA sponge of miR-302b to promote HCC progression via activation EGFR-PI3K-AKT signaling pathway.
    Title: LncUBE2R2-AS1 acts as a microRNA sponge of miR-302b to promote HCC progression via activation EGFR-PI3K-AKT signaling pathway.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • long intergenic non-protein coding RNA 1251

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_001337.2 

    Range
    126515..131956 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. NR_170201.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489

  2. NR_170202.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489, AL358573

  3. NR_170203.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489, AL358573

  4. NR_170204.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489, AL358573

  5. NR_170205.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489, AL358573

  6. NR_170206.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489, AL358573

  7. NR_170207.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489, AL358573
    Related
    ENST00000705030.1

  8. NR_170208.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489, AL358573

  9. NR_170209.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489, AL358573

  10. NR_170210.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489, AL358573

  11. NR_170211.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489, AL358573

  12. NR_170212.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489

  13. NR_170213.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489, AL358573

  14. NR_170215.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489, AL358573

  15. NR_170216.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL139113, AL356489, AL358573

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    33724085..33818868 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    33742642..33837455 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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