U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PRKCA-AS1 PRKCA antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 101928001, updated on 10-Oct-2023

Summary

Go to the top of the page Help
Official Symbol
PRKCA-AS1provided by HGNC
Official Full Name
PRKCA antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:51347
See related
AllianceGenome:HGNC:51347
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
17q24.2
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (66398069..66416854, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (67267789..67286611, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (64394187..64412972, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 14325 Neighboring gene RNA, 5S ribosomal pseudogene 444 Neighboring gene CRISPRi-validated cis-regulatory element chr17.4440 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:64299525-64300026 Neighboring gene Sharpr-MPRA regulatory region 4334 Neighboring gene Sharpr-MPRA regulatory region 10613 Neighboring gene protein kinase C alpha Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:64356585-64357085 Neighboring gene MPRA-validated peak2943 silencer Neighboring gene RNA, 7SL, cytoplasmic 735, pseudogene Neighboring gene Sharpr-MPRA regulatory region 12714 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:64412459-64412958 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:64429852-64430049 Neighboring gene MPRA-validated peak2944 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12613 Neighboring gene Sharpr-MPRA regulatory region 4299 Neighboring gene Sharpr-MPRA regulatory region 12581 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12614 Neighboring gene Sharpr-MPRA regulatory region 12401 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:64529308-64529848 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8864 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:64544955-64545137 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:64547106-64547989 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:64573678-64574638 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:64597839-64598492 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:64598493-64599144 Neighboring gene RNA, U6 small nuclear 928, pseudogene Neighboring gene RNA, 5S ribosomal pseudogene 445

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Coordination of PRKCA/PRKCA-AS1 interplay facilitates DNA methyltransferase 1 recruitment on DNA methylation to affect protein kinase C alpha transcription in mitral valve of rheumatic heart disease. Xie Z, et al. Bioengineered, 2021 Dec. PMID 34482802, Free PMC Article
  2. Creation of genome-wide protein expression libraries using random activation of gene expression. Harrington JJ, et al. Nat Biotechnol, 2001 May. PMID 11329013
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Coordination of PRKCA/PRKCA-AS1 interplay facilitates DNA methyltransferase 1 recruitment on DNA methylation to affect protein kinase C alpha transcription in mitral valve of rheumatic heart disease.
    Title: Coordination of PRKCA/PRKCA-AS1 interplay facilitates DNA methyltransferase 1 recruitment on DNA methylation to affect protein kinase C alpha transcription in mitral valve of rheumatic heart disease.
Submit: New GeneRIF Correction

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_110822.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC009452, BC033554, BG183684, CR745158

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    66398069..66416854 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    67267789..67286611 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases