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FLOT1 flotillin 1 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 101926288, updated on 12-Jun-2024

Summary

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Gene symbol
FLOT1
Gene description
flotillin 1
See related
Ensembl:ENSMFAG00000002025
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See FLOT1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 4 NC_088378.1 (141916279..141927919)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 4 NC_052258.1 (30453928..30465556, complement)

Chromosome 4 - NC_088378.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC135970663 Neighboring gene immediate early response 3 Neighboring gene tubulin beta class I Neighboring gene mediator of DNA damage checkpoint 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rate of evolution in brain-expressed genes in humans and other primates. Wang HY, et al. PLoS Biol, 2007 Feb. PMID 17194215, Free PMC Article
  2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in positive regulation of cell junction assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell-cell adhesion mediated by cadherin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein kinase C signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of receptor internalization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of flotillin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
flotillin-1
Names
Flotillin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088378.1 Reference T2T-MFA8v1.0

    Range
    141916279..141927919
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005553612.4 → XP_005553669.1  flotillin-1 isoform X1

    See identical proteins and their annotated locations for XP_005553669.1

    UniProtKB/TrEMBL
    A0A2K5TX72, A0A8J8XNG8, G7P4M4
    Related
    ENSMFAP00000004671.1
    Conserved Domains (2) summary
    COG2268
    Location:4 → 419
    YqiK; Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]
    cd03399
    Location:30 → 175
    SPFH_flotillin; Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

  2. XM_065544240.1 → XP_065400312.1  flotillin-1 isoform X3

  3. XM_065544239.1 → XP_065400311.1  flotillin-1 isoform X2

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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