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LIPA lipase A, lysosomal acid type [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 101926160, updated on 18-Sep-2024

Summary

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Gene symbol
LIPA
Gene description
lipase A, lysosomal acid type
See related
Ensembl:ENSMFAG00000035936
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
LAL
Orthologs
human mouse all
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Genomic context

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See LIPA in Genome Data Viewer
Location:
chromosome: 9
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 9 NC_088383.1 (98104879..98144155, complement)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 9 NC_052263.1 (84791729..84829064, complement)

Chromosome 9 - NC_088383.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC135965151 Neighboring gene cholesterol 25-hydroxylase Neighboring gene uncharacterized LOC123566833 Neighboring gene interferon induced protein with tetratricopeptide repeats 2 Neighboring gene interferon induced protein with tetratricopeptide repeats 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs. Osada N, et al. Mol Biol Evol, 2005 Oct. PMID 15944441
  2. Rate of evolution in brain-expressed genes in humans and other primates. Wang HY, et al. PLoS Biol, 2007 Feb. PMID 17194215, Free PMC Article
  3. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables sterol ester esterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in sterol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lysosomal acid lipase/cholesteryl ester hydrolase
Names
Acid cholesteryl ester hydrolase
Cholesteryl esterase
Lysosomal acid lipase/cholesteryl ester hydrolase
Sterol esterase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088383.1 Reference T2T-MFA8v1.0

    Range
    98104879..98144155 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005565904.4 → XP_005565961.3  lysosomal acid lipase/cholesteryl ester hydrolase

  2. XM_005565905.4 → XP_005565962.3  lysosomal acid lipase/cholesteryl ester hydrolase

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4R4S5.1 GenPept UniProtKB/Swiss-Prot:Q4R4S5

Gene LinkOut

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