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HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 101926043, updated on 12-Jun-2024

Summary

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Gene symbol
HMGCS1
Gene description
3-hydroxy-3-methylglutaryl-CoA synthase 1
See related
Ensembl:ENSMFAG00000035333
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See HMGCS1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 6 NC_088380.1 (43742459..43766607, complement)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 6 NC_052260.1 (43179986..43198611, complement)

Chromosome 6 - NC_088380.1Genomic Context describing neighboring genes Neighboring gene spermine synthase-like Neighboring gene NIM1 serine/threonine protein kinase Neighboring gene tubulin alpha-1C chain-like Neighboring gene large ribosomal subunit protein P1-like Neighboring gene uncharacterized LOC135971279 Neighboring gene C-C motif chemokine ligand 28 Neighboring gene transmembrane protein 267

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs. Osada N, et al. Mol Biol Evol, 2005 Oct. PMID 15944441
  2. Rate of evolution in brain-expressed genes in humans and other primates. Wang HY, et al. PLoS Biol, 2007 Feb. PMID 17194215, Free PMC Article
  3. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase, cytoplasmic
Names
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
XP_045250688.1
XP_065402294.1
XP_065402295.1
XP_065402296.1
XP_065402297.1
XP_065402298.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088380.1 Reference T2T-MFA8v1.0

    Range
    43742459..43766607 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_065546223.1 → XP_065402295.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

  2. XM_065546222.1 → XP_065402294.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

  3. XM_045394753.2 → XP_045250688.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

  4. XM_065546224.1 → XP_065402296.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

  5. XM_065546226.1 → XP_065402298.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

  6. XM_065546225.1 → XP_065402297.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001284609.1: Suppressed sequence

    Description
    NM_001284609.1: This RefSeq record was removed as a result of standard genome annotation processing. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
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