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IDH1 isocitrate dehydrogenase (NADP(+)) 1 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 101925790, updated on 12-Jun-2024

Summary

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Gene symbol
IDH1
Gene description
isocitrate dehydrogenase (NADP(+)) 1
See related
Ensembl:ENSMFAG00000037839
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 12 NC_088386.1 (104178252..104196840, complement)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 12 NC_052266.1 (93418498..93437083, complement)

Chromosome 12 - NC_088386.1Genomic Context describing neighboring genes Neighboring gene chromosome 12 C2orf80 homolog Neighboring gene translationally-controlled tumor protein-like Neighboring gene myosin light chain 6B-like Neighboring gene phosphoinositide kinase, FYVE-type zinc finger containing Neighboring gene parathyroid hormone 2 receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rate of evolution in brain-expressed genes in humans and other primates. Wang HY, et al. PLoS Biol, 2007 Feb. PMID 17194215, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables isocitrate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in NADP metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in isocitrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
isocitrate dehydrogenase [NADP] cytoplasmic
Names
isocitrate dehydrogenase (NADP(+)) 1, cytosolic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088386.1 Reference T2T-MFA8v1.0

    Range
    104178252..104196840 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005574098.4 → XP_005574155.1  isocitrate dehydrogenase [NADP] cytoplasmic

    See identical proteins and their annotated locations for XP_005574155.1

    UniProtKB/TrEMBL
    A0A2K5WJA5, G7PLB1
    Related
    ENSMFAP00000037210.1
    Conserved Domains (1) summary
    PTZ00435
    Location:1 → 411
    PTZ00435; isocitrate dehydrogenase; Provisional

  2. XM_045367608.2 → XP_045223543.1  isocitrate dehydrogenase [NADP] cytoplasmic

    UniProtKB/TrEMBL
    A0A2K5WJA5, G7PLB1
    Conserved Domains (1) summary
    PTZ00435
    Location:1 → 411
    PTZ00435; isocitrate dehydrogenase; Provisional

  3. XM_045367607.2 → XP_045223542.1  isocitrate dehydrogenase [NADP] cytoplasmic

    UniProtKB/TrEMBL
    A0A2K5WJA5, G7PLB1
    Conserved Domains (1) summary
    PTZ00435
    Location:1 → 411
    PTZ00435; isocitrate dehydrogenase; Provisional

  4. XM_005574099.4 → XP_005574156.1  isocitrate dehydrogenase [NADP] cytoplasmic

    See identical proteins and their annotated locations for XP_005574156.1

    UniProtKB/TrEMBL
    A0A2K5WJA5, G7PLB1
    Related
    ENSMFAP00000037216.1
    Conserved Domains (1) summary
    PTZ00435
    Location:1 → 411
    PTZ00435; isocitrate dehydrogenase; Provisional
Nucleotide Protein
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