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CAPN3 calpain 3 [ Falco peregrinus (peregrine falcon) ]

Gene ID: 101924532, updated on 3-Aug-2024

Summary

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Gene symbol
CAPN3
Gene description
calpain 3
See related
EnsemblRapid:ENSFPEG00020012042
Gene type
protein coding
RefSeq status
MODEL
Organism
Falco peregrinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Falconiformes; Falconidae; Falco
Orthologs
human mouse all
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Genomic context

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See CAPN3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2023_04 current bFalPer1.pri (GCF_023634155.1) 1 NC_073721.1 (81207750..81239323, complement)
102 previous assembly F_peregrinus_v1.0 (GCF_000337955.1) Unplaced Scaffold NW_004930506.1 (1442864..1474566, complement)

Chromosome 1 - NC_073721.1Genomic Context describing neighboring genes Neighboring gene synaptosome associated protein 23 Neighboring gene zinc finger protein 106 Neighboring gene glucosidase alpha, neutral C Neighboring gene transmembrane protein 87A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3
Names
calpain 3, (p94)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_023634155.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bFalPer1.pri Primary Assembly

Genomic

  1. NC_073721.1 Reference bFalPer1.pri Primary Assembly

    Range
    81207750..81239323 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027795784.2 → XP_027651585.1  calpain-3 isoform X2

    Related
    ENSFPEP00020017746.1, ENSFPET00020018393.1
    Conserved Domains (3) summary
    cd16190
    Location:603 → 771
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:70 → 409
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:430 → 568
    Calpain_III; Calpain large subunit, domain III

  2. XM_027795783.2 → XP_027651584.1  calpain-3 isoform X1

    Conserved Domains (3) summary
    cd16190
    Location:609 → 777
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:70 → 409
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:430 → 568
    Calpain_III; Calpain large subunit, domain III

  3. XM_027795789.2 → XP_027651590.1  calpain-3 isoform X7

    Conserved Domains (4) summary
    cd16190
    Location:643 → 811
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:70 → 409
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:430 → 568
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:577 → 643
    Calpain_u2; Unstructured region on Calpain-3

  4. XM_027795788.2 → XP_027651589.1  calpain-3 isoform X6

    Conserved Domains (4) summary
    cd16190
    Location:647 → 815
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:70 → 409
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:430 → 568
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:577 → 647
    Calpain_u2; Unstructured region on Calpain-3

  5. XM_027795786.2 → XP_027651587.1  calpain-3 isoform X4

    Conserved Domains (3) summary
    cd16190
    Location:326 → 494
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam01067
    Location:147 → 285
    Calpain_III; Calpain large subunit, domain III
    cl00051
    Location:34 → 126
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.

  6. XM_055816709.1 → XP_055672684.1  calpain-3 isoform X5

  7. XM_055816695.1 → XP_055672670.1  calpain-3 isoform X3

Nucleotide Protein
Heading Accession and Version

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