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TJP2 tight junction protein 2 [ Falco peregrinus (peregrine falcon) ]

Gene ID: 101913859, updated on 3-Aug-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
See related
EnsemblRapid:ENSFPEG00020007169
Gene type
protein coding
RefSeq status
MODEL
Organism
Falco peregrinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Falconiformes; Falconidae; Falco
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: Z
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2023_04 current bFalPer1.pri (GCF_023634155.1) Z NC_073739.1 (47973326..48039497)
102 previous assembly F_peregrinus_v1.0 (GCF_000337955.1) Unplaced Scaffold NW_004930340.1 (810911..876915, complement)

Chromosome Z - NC_073739.1Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 beta Neighboring gene frataxin Neighboring gene uncharacterized LOC114013499 Neighboring gene interferon omega-1 Neighboring gene 3-hydroxyacyl-CoA dehydratase 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_023634155.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bFalPer1.pri Primary Assembly

Genomic

  1. NC_073739.1 Reference bFalPer1.pri Primary Assembly

    Range
    47973326..48039497
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_055791703.1 → XP_055647678.1  tight junction protein ZO-2 isoform X5

  2. XM_027793558.2 → XP_027649359.1  tight junction protein ZO-2 isoform X5

    Conserved Domains (5) summary
    cd12027
    Location:573 → 635
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:669 → 848
    GuKc; Guanylate kinase homologues
    smart00228
    Location:273 → 351
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:162 → 255
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  3. XM_055791704.1 → XP_055647679.1  tight junction protein ZO-2 isoform X5

  4. XM_055791705.1 → XP_055647680.1  tight junction protein ZO-2 isoform X5

    Related
    ENSFPEP00020010390.1, ENSFPET00020010753.1

  5. XM_027793555.2 → XP_027649356.1  tight junction protein ZO-2 isoform X1

    Conserved Domains (5) summary
    cd12027
    Location:654 → 716
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:750 → 929
    GuKc; Guanylate kinase homologues
    smart00228
    Location:354 → 432
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:90 → 175
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:243 → 336
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  6. XM_055791702.1 → XP_055647677.1  tight junction protein ZO-2 isoform X4

  7. XM_027793556.2 → XP_027649357.1  tight junction protein ZO-2 isoform X2

  8. XM_055791701.1 → XP_055647676.1  tight junction protein ZO-2 isoform X3

Nucleotide Protein
Heading Accession and Version

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