mtmr11 myotubularin related protein 11 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mtmr11provided by ZNC
Official Full Name: myotubularin related protein 11provided by ZNC
Primary source: ZFIN:ZDB-GENE-130530-726
See related: Ensembl:ENSDARG00000069755 AllianceGenome:ZFIN:ZDB-GENE-130530-726
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fj83e02
Summary: Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to be active in cytoplasm. Orthologous to human MTMR11 (myotubularin related protein 11). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (46000981..46082219)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (46034265..46115503)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables phosphatidylinositol-3-phosphate phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in phosphatidylinositol dephosphorylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: myotubularin-related protein 11

Names: zmp:0000000723

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001326441.1 → NP_001313370.1 myotubularin-related protein 11

Status: VALIDATED

Source sequence(s)

BX537142, CR848792, CR933818

UniProtKB/TrEMBL

A0A8M1P3C0, E7F7E6

Related

ENSDARP00000139216.1, ENSDART00000162393.2

Conserved Domains (3) summary

cd15790
Location:41 → 162

PH-GRAM_MTMR11; Myotubularian (MTM) related 11 protein (MTMR11) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain

pfam12578
Location:578 → 703

3-PAP; Myotubularin-associated protein

cl21483
Location:210 → 495

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...