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Nr1h4 nuclear receptor subfamily 1 group H member 4 [ Mesocricetus auratus (golden hamster) ]

Gene ID: 101828436, updated on 8-Mar-2024

Summary

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Gene symbol
Nr1h4
Gene description
nuclear receptor subfamily 1 group H member 4
See related
EnsemblRapid:ENSMAUG00000011325
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mesocricetus auratus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Mesocricetus
Orthologs
human mouse all
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Genomic context

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See Nr1h4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
103 current BCM_Maur_2.0 (GCF_017639785.1) Unplaced Scaffold NW_024429195.1 (78122590..78191697)
102 previous assembly MesAur1.0 (GCF_000349665.1) Unplaced Scaffold NW_004801615.1 (2927274..2996514, complement)

NW_024429195.1Genomic Context describing neighboring genes Neighboring gene SCY1 like pseudokinase 2 Neighboring gene solute carrier family 17 member 8 Neighboring gene uncharacterized LOC121143319 Neighboring gene growth arrest specific 2 like 3 Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters. Huber RM, et al. Gene, 2002 May 15. PMID 12062799
  2. Transcriptome sequencing and development of an expression microarray platform for liver infection in adenovirus type 5-infected Syrian golden hamsters. Ying B, et al. Virology, 2015 Nov. PMID 26319212, Free PMC Article
  3. De novo assembly, annotation, and characterization of the whole brain transcriptome of male and female Syrian hamsters. McCann KE, et al. Sci Rep, 2017 Jan 10. PMID 28071753, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables bile acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bile acid signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bile acid receptor
Names
farnesoid-X-receptor alpha
farnesoid-X-receptor beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001281573.1 → NP_001268502.1  bile acid receptor

    See identical proteins and their annotated locations for NP_001268502.1

    Status: PROVISIONAL

    Source sequence(s)
    AF478444
    UniProtKB/TrEMBL
    Q8K473
    Related
    ENSMAUP00000010435.1, ENSMAUT00000014307.2
    Conserved Domains (2) summary
    cd06936
    Location:262 → 482
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:135 → 222
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

RefSeqs of Annotated Genomes: Mesocricetus auratus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCM_Maur_2.0 Primary Assembly

Genomic

  1. NW_024429195.1 Reference BCM_Maur_2.0 Primary Assembly

    Range
    78122590..78191697
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013111821.3 → XP_012967275.1  bile acid receptor isoform X2

    See identical proteins and their annotated locations for XP_012967275.1

    UniProtKB/TrEMBL
    Q8K475
    Related
    ENSMAUP00000010431.1, ENSMAUT00000014303.2
    Conserved Domains (2) summary
    cd06936
    Location:248 → 468
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cl02596
    Location:121 → 208
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  2. XM_013111822.3 → XP_012967276.1  bile acid receptor isoform X3

    See identical proteins and their annotated locations for XP_012967276.1

    UniProtKB/TrEMBL
    Q8K476
    Conserved Domains (2) summary
    cd06936
    Location:244 → 464
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:121 → 204
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

  3. XM_013111820.3 → XP_012967274.1  bile acid receptor isoform X1

    See identical proteins and their annotated locations for XP_012967274.1

    UniProtKB/TrEMBL
    Q8K474
    Conserved Domains (2) summary
    cd06936
    Location:258 → 478
    NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
    cd06962
    Location:135 → 218
    NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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