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GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase [ Ficedula albicollis (Collared flycatcher) ]

Gene ID: 101817440, updated on 3-Aug-2024

Summary

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Gene symbol
GNE
Gene description
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
See related
Ensembl:ENSFALG00000001008
Gene type
protein coding
RefSeq status
MODEL
Organism
Ficedula albicollis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Muscicapidae; Ficedula
Orthologs
human mouse all
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Genomic context

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See GNE in Genome Data Viewer
Location:
chromosome: Z
Exon count:
15
Annotation release Status Assembly Chr Location
101 current FicAlb1.5 (GCF_000247815.1) Z NC_021700.1 (41824225..41850146)

Chromosome Z - NC_021700.1Genomic Context describing neighboring genes Neighboring gene complexin 1 Neighboring gene uncharacterized LOC101818024 Neighboring gene clathrin light chain A Neighboring gene N-acetylneuraminate synthase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_021700.1 Chromosome Z Reference FicAlb1.5 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables N-acylmannosamine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables UDP-N-acetylglucosamine 2-epimerase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in UDP-N-acetylglucosamine metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ficedula albicollis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference FicAlb1.5 Primary Assembly

Genomic

  1. NC_021700.1 Reference FicAlb1.5 Primary Assembly

    Range
    41824225..41850146
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005061042.1 → XP_005061099.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X3

    See identical proteins and their annotated locations for XP_005061099.1

    UniProtKB/TrEMBL
    U3JE41
    Conserved Domains (4) summary
    cd03786
    Location:11 → 375
    GT1_UDP-GlcNAc_2-Epimerase; Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues ...
    COG1940
    Location:409 → 721
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:11 → 374
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing
    cl17037
    Location:410 → 715
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  2. XM_005061043.1 → XP_005061100.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X3

    See identical proteins and their annotated locations for XP_005061100.1

    UniProtKB/TrEMBL
    U3JE41
    Conserved Domains (4) summary
    cd03786
    Location:11 → 375
    GT1_UDP-GlcNAc_2-Epimerase; Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues ...
    COG1940
    Location:409 → 721
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:11 → 374
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing
    cl17037
    Location:410 → 715
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  3. XM_005061041.1 → XP_005061098.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1

    See identical proteins and their annotated locations for XP_005061098.1

    UniProtKB/TrEMBL
    U3JE41
    Related
    ENSFALP00000001045.1, ENSFALT00000001050.2
    Conserved Domains (4) summary
    cd03786
    Location:11 → 375
    GT1_UDP-GlcNAc_2-Epimerase; Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues ...
    COG1940
    Location:409 → 721
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:11 → 374
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing
    cl17037
    Location:410 → 715
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  4. XM_016304771.1 → XP_016160257.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X2

    UniProtKB/TrEMBL
    U3JE41
    Conserved Domains (4) summary
    cd03786
    Location:11 → 375
    GT1_UDP-GlcNAc_2-Epimerase; Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues ...
    COG1940
    Location:409 → 721
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:11 → 374
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing
    cl17037
    Location:410 → 715
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
Nucleotide Protein
Heading Accession and Version

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