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LOC101740082 sericin 1-like [ Bombyx mori (domestic silkworm) ]

Gene ID: 101740082, updated on 23-Apr-2024

Summary

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Gene symbol
LOC101740082
Gene description
sericin 1-like
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bombyx mori
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea; Bombycidae; Bombycinae; Bombyx
Also known as
ser1; sericin1B
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Genomic context

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See LOC101740082 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_01 current ASM3026992v2 (GCF_030269925.1) 11 NC_085117.1 (2513096..2543046)
103 previous assembly Bmori_2016v1.0 (GCF_014905235.1) 11 NC_051368.1 (2534653..2564617)

Chromosome 11 - NC_085117.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119629147 Neighboring gene uncharacterized LOC105841987 Neighboring gene pheromone biosynthesis activating neuropeptide Neighboring gene uncharacterized LOC101740482 Neighboring gene microRNA mir-3357 Neighboring gene leishmanolysin-like peptidase, invadolysin Neighboring gene uncharacterized LOC105842074

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Bmo-miR-2780a regulates the expression of the sericin-1 gene of Bombyx mori. Qian P, et al. Arch Insect Biochem Physiol, 2020 Feb. PMID 31701579
  2. Enhancer activity of Helitron in sericin-1 gene promoter from Bombyx mori. Huang K, et al. Insect Sci, 2016 Jun. PMID 27067405
  3. Structural analysis of sericin genes. Homologies with fibroin gene in the 5' flanking nucleotide sequences. Okamoto H, et al. J Biol Chem, 1982 Dec 25. PMID 6294094
  4. The effects of Bombyx mori silk strain and extraction time on the molecular and biological characteristics of sericin. Siritientong T, et al. Biosci Biotechnol Biochem, 2016. PMID 26399155
  5. Structure and organization of the Bombyx mori sericin 1 gene and of the sericins 1 deduced from the sequence of the Ser 1B cDNA. Garel A, et al. Insect Biochem Mol Biol, 1997 May. PMID 9219370

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Effects of Osiris9a on Silk Properties in Bombyx mori Determined by Transgenic Overexpression.
    Title: Effects of Osiris9a on Silk Properties in Bombyx mori Determined by Transgenic Overexpression.
  2. Insights into regulatory characteristics of the promoters of Sericin 1 and Sericin 3 in transgenic silkworms.
    Title: Insights into regulatory characteristics of the promoters of Sericin 1 and Sericin 3 in transgenic silkworms.
  3. The target gene (Ser-1) was significantly decreased by miR-2780a compared with the control group (p < .05), thus indicating that bmo-miR-2780a might negatively regulate the expression of Ser-1.
    Title: Bmo-miR-2780a regulates the expression of the sericin-1 gene of Bombyx mori.
  4. Ser-1 is located near the distal end of the 11th linkage group, relatively at the 12.5+/-1.4 position in pachytene stage.
    Title: Chromosomal localization of silkworm (Bombyx mori) sericin gene 1 and chymotrypsin inhibitor 13 using fluorescence in situ hybridization.
  5. Antp is a Hox transcription factor that regulates sericin-1 gene expression in the terminal differentiated silk gland of Bombyx mori
    Title: Hox transcription factor Antp regulates sericin-1 gene expression in the terminal differentiated silk gland of Bombyx mori.
  6. The molecular and biological characteristics of sericin depend on the Bombyx mori silk strain and extraction time.
    Title: The effects of Bombyx mori silk strain and extraction time on the molecular and biological characteristics of sericin.
  7. Antennapedia regulates expression of sericin-1, a major silk protein gene, in the silk gland.
    Title: A Hox Gene, Antennapedia, Regulates Expression of Multiple Major Silk Protein Genes in the Silkworm Bombyx mori.
  8. Bmhel-8 in the sericin-1 promoter exhibits enhancer activity. Bmhel-8 displays enhancer activity in a sericin-1 promoter-driven gene expression system but does not regulate the tissue-specific expression of sericin-1.
    Title: Enhancer activity of Helitron in sericin-1 gene promoter from Bombyx mori.
  9. These results suggest that POU-M1 is involved in restricting the anterior boundary of the sericin-1-expressing region in the silk gland by inhibiting the binding of the transcriptional activator to the promoter elements.
    Title: Inhibition of the binding of MSG-intermolt-specific complex, MIC, to the sericin-1 gene promoter and sericin-1 gene expression by POU-M1/SGF-3.
  10. Novel enhancer and promoter elements are indispensable for the tissue-specific expression of the sericin-1 gene of the silkworm Bombyx mori.
    Title: Novel enhancer and promoter elements indispensable for the tissue-specific expression of the sericin-1 gene of the silkworm Bombyx mori.
Submit: New GeneRIF Correction

General protein information

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Preferred Names
sericin 1
Names
sericin 1A
sericin 1A'
sericin 1B
silk gum protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044041.2 → NP_001037506.2  sericin 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AP028181
    UniProtKB/TrEMBL
    A0A8R1XC65

RefSeqs of Annotated Genomes: GCF_030269925.1-RS_2024_01

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM3026992v2 Primary Assembly

Genomic

  1. NC_085117.1 Reference ASM3026992v2 Primary Assembly

    Range
    2513096..2543046
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038013610.2 → XP_037869538.1  sericin 1 isoform X1

    UniProtKB/TrEMBL
    A0A8R2M074

  2. XM_038013611.2 → XP_037869539.1  sericin 1 isoform X2

    UniProtKB/TrEMBL
    A0A8R2LZ38

  3. XM_012692169.4 → XP_012547623.2  sericin 1 isoform X22

    UniProtKB/TrEMBL
    A0A8R2C6V4
    Conserved Domains (1) summary
    NF033609
    Location:98 → 452
    MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA

  4. XM_038013615.2 → XP_037869543.1  sericin 1 isoform X7

    UniProtKB/TrEMBL
    A0A8R2LYV7

  5. XM_038013617.2 → XP_037869545.1  sericin 1 isoform X8

    UniProtKB/TrEMBL
    A0A8R2LXH4

  6. XM_038013630.2 → XP_037869558.1  sericin 1 isoform X26

    UniProtKB/TrEMBL
    A0A8R2M086
    Conserved Domains (1) summary
    NF033609
    Location:98 → 452
    MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA

  7. XM_038013612.2 → XP_037869540.1  sericin 1 isoform X4

    UniProtKB/TrEMBL
    A0A8R2LZ50

  8. XM_062670824.1 → XP_062526808.1  sericin 1 isoform X24

  9. XM_021349665.3 → XP_021205340.2  sericin 1 isoform X28

    UniProtKB/TrEMBL
    A0A8R2DLE6
    Conserved Domains (1) summary
    NF033609
    Location:98 → 452
    MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA

  10. XM_062670816.1 → XP_062526800.1  sericin 1 isoform X3

  11. XM_062670823.1 → XP_062526807.1  sericin 1 isoform X23

  12. XM_062670826.1 → XP_062526810.1  sericin 1 isoform X27

  13. XM_062670818.1 → XP_062526802.1  sericin 1 isoform X5

  14. XM_062670827.1 → XP_062526811.1  sericin 1 isoform X29

  15. XM_038013613.2 → XP_037869541.1  sericin 1 isoform X6

    UniProtKB/TrEMBL
    A0A8R2LXJ2

  16. XM_021349658.3 → XP_021205333.2  sericin 1 isoform X25

    UniProtKB/TrEMBL
    A0A8R2DMC5
    Conserved Domains (1) summary
    NF033609
    Location:98 → 452
    MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA

  17. XM_038013620.2 → XP_037869548.1  sericin 1 isoform X10

    UniProtKB/TrEMBL
    A0A8R2QX88

  18. XM_038013621.2 → XP_037869549.1  sericin 1 isoform X11

    UniProtKB/TrEMBL
    A0A8R2QV45

  19. XM_021349667.3 → XP_021205342.2  sericin 1 isoform X30

    UniProtKB/TrEMBL
    A0A8R2DN43

  20. XM_038013618.2 → XP_037869546.1  sericin 1 isoform X9

    UniProtKB/TrEMBL
    A0A8R2LYF5

  21. XM_038013622.2 → XP_037869550.1  sericin 1 isoform X12

    UniProtKB/TrEMBL
    A0A8R2QUV5

  22. XM_062670819.1 → XP_062526803.1  sericin 1 isoform X13

  23. XM_021349673.3 → XP_021205348.2  sericin 1 isoform X31

    UniProtKB/TrEMBL
    A0A8R2HMN8
    Conserved Domains (2) summary
    NF033609
    Location:163 → 521
    MSCRAMM_ClfA; MSCRAMM family adhesin clumping factor ClfA
    NF033845
    Location:364 → 580
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

  24. XM_038013623.2 → XP_037869551.1  sericin 1 isoform X14

    UniProtKB/TrEMBL
    A0A8R2QUR5

  25. XM_038013624.2 → XP_037869552.1  sericin 1 isoform X16

    UniProtKB/TrEMBL
    A0A8R2QW27

  26. XM_038013625.2 → XP_037869553.1  sericin 1 isoform X18

    UniProtKB/TrEMBL
    A0A8R2QZ28

  27. XM_038013628.2 → XP_037869556.1  sericin 1 isoform X21

    UniProtKB/TrEMBL
    A0A8R2R0V7

  28. XM_038013627.2 → XP_037869555.1  sericin 1 isoform X20

    UniProtKB/TrEMBL
    A0A8R2R089

  29. XM_062670821.1 → XP_062526805.1  sericin 1 isoform X15

  30. XM_062670822.1 → XP_062526806.1  sericin 1 isoform X17

  31. XM_038013626.2 → XP_037869554.1  sericin 1 isoform X19

    UniProtKB/TrEMBL
    A0A8R2QZ19

  32. XM_038013631.2 → XP_037869559.1  sericin 1 isoform X32

    UniProtKB/TrEMBL
    A0A8R2LZ48
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P07856.2 GenPept UniProtKB/Swiss-Prot:P07856

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