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Rnf144b ring finger protein 144B [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101701481, updated on 8-Mar-2024

Summary

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Gene symbol
Rnf144b
Gene description
ring finger protein 144B
Locus tag
GW7_07642
See related
Ensembl:ENSHGLG00000006675
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Rnf144b in Genome Data Viewer
Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624756.1 (8210829..8409509, complement)

NW_004624756.1Genomic Context describing neighboring genes Neighboring gene NEDD8-activating enzyme E1 catalytic subunit pseudogene Neighboring gene RNA-binding protein with serine-rich domain 1 pseudogene Neighboring gene V-type proton ATPase subunit G 1 pseudogene Neighboring gene translation machinery-associated protein 7 pseudogene Neighboring gene zinc finger protein 160-like Neighboring gene DEK proto-oncogene Neighboring gene lysine demethylase 1B

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624756 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin conjugating enzyme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase RNF144B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624756.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    8210829..8409509 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021260583.1 → XP_021116242.1  E3 ubiquitin-protein ligase RNF144B isoform X4

    UniProtKB/TrEMBL
    A0A0P6JAR2
    Conserved Domains (3) summary
    smart00647
    Location:112 → 177
    IBR; In Between Ring fingers
    pfam01485
    Location:201 → 236
    IBR; IBR domain, a half RING-finger domain
    cd16778
    Location:28 → 84
    mRING-HC-C4C4_RBR_RNF144B; Modified RING finger, HC subclass (C4C4-type), found in RING finger protein 144B (RNF144B)

  2. XM_021260584.1 → XP_021116243.1  E3 ubiquitin-protein ligase RNF144B isoform X4

    UniProtKB/TrEMBL
    A0A0P6JAR2
    Conserved Domains (3) summary
    smart00647
    Location:112 → 177
    IBR; In Between Ring fingers
    pfam01485
    Location:201 → 236
    IBR; IBR domain, a half RING-finger domain
    cd16778
    Location:28 → 84
    mRING-HC-C4C4_RBR_RNF144B; Modified RING finger, HC subclass (C4C4-type), found in RING finger protein 144B (RNF144B)

  3. XM_021260582.1 → XP_021116241.1  E3 ubiquitin-protein ligase RNF144B isoform X4

    UniProtKB/TrEMBL
    A0A0P6JAR2
    Conserved Domains (3) summary
    smart00647
    Location:112 → 177
    IBR; In Between Ring fingers
    pfam01485
    Location:201 → 236
    IBR; IBR domain, a half RING-finger domain
    cd16778
    Location:28 → 84
    mRING-HC-C4C4_RBR_RNF144B; Modified RING finger, HC subclass (C4C4-type), found in RING finger protein 144B (RNF144B)

  4. XM_021260579.1 → XP_021116238.1  E3 ubiquitin-protein ligase RNF144B isoform X1

    UniProtKB/TrEMBL
    A0A0P6JAR2
    Conserved Domains (3) summary
    smart00647
    Location:147 → 212
    IBR; In Between Ring fingers
    pfam01485
    Location:236 → 271
    IBR; IBR domain, a half RING-finger domain
    cd16778
    Location:63 → 119
    mRING-HC-C4C4_RBR_RNF144B; Modified RING finger, HC subclass (C4C4-type), found in RING finger protein 144B (RNF144B)

  5. XM_021260581.1 → XP_021116240.1  E3 ubiquitin-protein ligase RNF144B isoform X3

    UniProtKB/TrEMBL
    A0A0P6JAR2
    Related
    ENSHGLP00000009309.1, ENSHGLT00000009410.1
    Conserved Domains (3) summary
    smart00647
    Location:136 → 201
    IBR; In Between Ring fingers
    pfam01485
    Location:225 → 260
    IBR; IBR domain, a half RING-finger domain
    cd16778
    Location:63 → 119
    mRING-HC-C4C4_RBR_RNF144B; Modified RING finger, HC subclass (C4C4-type), found in RING finger protein 144B (RNF144B)

  6. XM_021260580.1 → XP_021116239.1  E3 ubiquitin-protein ligase RNF144B isoform X2

    UniProtKB/TrEMBL
    A0A0P6JAR2
    Conserved Domains (3) summary
    smart00647
    Location:137 → 202
    IBR; In Between Ring fingers
    pfam01485
    Location:226 → 261
    IBR; IBR domain, a half RING-finger domain
    cd16778
    Location:53 → 109
    mRING-HC-C4C4_RBR_RNF144B; Modified RING finger, HC subclass (C4C4-type), found in RING finger protein 144B (RNF144B)

  7. XM_021260585.1 → XP_021116244.1  E3 ubiquitin-protein ligase RNF144B isoform X5

    UniProtKB/TrEMBL
    G5B713
    Conserved Domains (3) summary
    smart00647
    Location:85 → 150
    IBR; In Between Ring fingers
    pfam01485
    Location:174 → 209
    IBR; IBR domain, a half RING-finger domain
    cl17238
    Location:29 → 57
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  8. XM_013073271.2 → XP_012928725.1  E3 ubiquitin-protein ligase RNF144B isoform X6

    UniProtKB/TrEMBL
    G5B713
    Conserved Domains (2) summary
    smart00647
    Location:74 → 139
    IBR; In Between Ring fingers
    pfam01485
    Location:163 → 198
    IBR; IBR domain, a half RING-finger domain
Nucleotide Protein
Heading Accession and Version

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