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PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial [ Mustela putorius furo (domestic ferret) ]

Gene ID: 101693939, updated on 8-Mar-2024

Summary

Gene symbol
PCK2
Gene description
phosphoenolpyruvate carboxykinase 2, mitochondrial
See related
Ensembl:ENSMPUG00000006229
Gene type
protein coding
RefSeq status
MODEL
Organism
Mustela putorius furo (sub-species: furo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Mustela
Orthologs
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Genomic context

See PCK2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
102 current ASM1176430v1.1 (GCF_011764305.1) Unplaced Scaffold NW_025422047.1 (21581149..21589739)
101 previous assembly MusPutFur1.0 (GCF_000215625.1) Unplaced Scaffold NW_004569190.1 (6667540..6678079, complement)

NW_025422047.1Genomic Context describing neighboring genes Neighboring gene copine 6 Neighboring gene neural retina leucine zipper Neighboring gene uncharacterized LOC123386918 Neighboring gene DDB1 and CUL4 associated factor 11

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables phosphoenolpyruvate carboxykinase (GTP) activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to dexamethasone stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glycerol biosynthetic process from pyruvate IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in hepatocyte differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in propionate catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to starvation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
phosphoenolpyruvate carboxykinase [GTP], mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mustela putorius furo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1176430v1.1 Primary Assembly

Genomic

  1. NW_025422047.1 Reference ASM1176430v1.1 Primary Assembly

    Range
    21581149..21589739
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004755276.3XP_004755333.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8U0MTB6, G9KFI3
    Related
    ENSMPUP00000006176.1
    Conserved Domains (1) summary
    cd00819
    Location:44633
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...
  2. XM_045067611.1XP_044923546.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8U0URA8, G9KFI3
    Conserved Domains (1) summary
    cd00819
    Location:18607
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...