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TMTC4 transmembrane O-mannosyltransferase targeting cadherins 4 [ Mustela putorius furo (domestic ferret) ]

Gene ID: 101690331, updated on 8-Mar-2024

Summary

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Gene symbol
TMTC4
Gene description
transmembrane O-mannosyltransferase targeting cadherins 4
See related
Ensembl:ENSMPUG00000011315
Gene type
protein coding
RefSeq status
MODEL
Organism
Mustela putorius furo (sub-species: furo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Mustela
Orthologs
human mouse all
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Genomic context

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See TMTC4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
102 current ASM1176430v1.1 (GCF_011764305.1) Unplaced Scaffold NW_025421412.1 (10503300..10567128)
101 previous assembly MusPutFur1.0 (GCF_000215625.1) Unplaced Scaffold NW_004569159.1 (10459143..10516374)

NW_025421412.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA72 Neighboring gene uncharacterized LOC123392407 Neighboring gene gamma-glutamylamine cyclotransferase Neighboring gene propionyl-CoA carboxylase subunit alpha Neighboring gene tubulin alpha chain, testis-specific-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptome sequencing and development of an expression microarray platform for the domestic ferret. Bruder CE, et al. BMC Genomics, 2010 Apr 19. PMID 20403183, Free PMC Article
  2. Sequencing, annotation, and characterization of the influenza ferret infectome. León AJ, et al. J Virol, 2013 Feb. PMID 23236062, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein O-linked mannosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein O-mannosyl-transferase TMTC4
Names
transmembrane and tetratricopeptide repeat containing 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mustela putorius furo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1176430v1.1 Primary Assembly

Genomic

  1. NW_025421412.1 Reference ASM1176430v1.1 Primary Assembly

    Range
    10503300..10567128
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045081353.1 → XP_044937288.1  protein O-mannosyl-transferase TMTC4 isoform X3

    UniProtKB/TrEMBL
    A0A8U0V3D3
    Conserved Domains (3) summary
    COG0457
    Location:450 → 688
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:482 → 510
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:294 → 366
    DUF1736; Domain of unknown function (DUF1736)

  2. XM_045081352.1 → XP_044937287.1  protein O-mannosyl-transferase TMTC4 isoform X2

    UniProtKB/TrEMBL
    A0A8U0S7B5, G9KUD2
    Conserved Domains (3) summary
    COG0457
    Location:449 → 712
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:481 → 509
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:293 → 365
    DUF1736; Domain of unknown function (DUF1736)

  3. XM_045081350.1 → XP_044937285.1  protein O-mannosyl-transferase TMTC4 isoform X1

    UniProtKB/TrEMBL
    G9KUD2, M3YIR6
    Conserved Domains (3) summary
    COG0457
    Location:450 → 713
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:482 → 510
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:294 → 366
    DUF1736; Domain of unknown function (DUF1736)

  4. XM_045081354.1 → XP_044937289.1  protein O-mannosyl-transferase TMTC4 isoform X1

    UniProtKB/TrEMBL
    G9KUD2, M3YIR6
    Conserved Domains (3) summary
    COG0457
    Location:450 → 713
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:482 → 510
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:294 → 366
    DUF1736; Domain of unknown function (DUF1736)

  5. XM_013053109.2 → XP_012908563.1  protein O-mannosyl-transferase TMTC4 isoform X4

    UniProtKB/TrEMBL
    A0A8U0NRT7, G9KUD2
    Conserved Domains (7) summary
    smart00028
    Location:480 → 513
    TPR; Tetratricopeptide repeats
    COG0457
    Location:346 → 609
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:378 → 406
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:446 → 479
    TPR_1; Tetratricopeptide repeat
    pfam07719
    Location:378 → 411
    TPR_2; Tetratricopeptide repeat
    pfam08409
    Location:188 → 262
    DUF1736; Domain of unknown function (DUF1736)
    pfam13431
    Location:400 → 433
    TPR_17; Tetratricopeptide repeat
Nucleotide Protein
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