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SHMT2 serine hydroxymethyltransferase 2 [ Mustela putorius furo (domestic ferret) ]

Gene ID: 101678444, updated on 8-Mar-2024

Summary

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Gene symbol
SHMT2
Gene description
serine hydroxymethyltransferase 2
See related
Ensembl:ENSMPUG00000001772
Gene type
protein coding
RefSeq status
MODEL
Organism
Mustela putorius furo (sub-species: furo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Mustela
Orthologs
human mouse all
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Genomic context

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See SHMT2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
102 current ASM1176430v1.1 (GCF_011764305.1) Unplaced Scaffold NW_025422127.1 (2558538..2563542)
101 previous assembly MusPutFur1.0 (GCF_000215625.1) Unplaced Scaffold NW_004569320.1 (1550149..1555149)

NW_025422127.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123389632 Neighboring gene LDL receptor related protein 1 Neighboring gene neurexophilin 4 Neighboring gene NDUFA4 mitochondrial complex associated like 2 Neighboring gene SH3 and cysteine rich domain 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De-novo transcriptome sequencing of a normalized cDNA pool from influenza infected ferrets. Camp JV, et al. PLoS One, 2012. PMID 22606336, Free PMC Article
  2. Sequencing, annotation, and characterization of the influenza ferret infectome. León AJ, et al. J Virol, 2013 Feb. PMID 23236062, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cobalt ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glycine hydroxymethyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mRNA 5'-UTR binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mRNA regulatory element binding translation repressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-serine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in folic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycine biosynthetic process from serine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein homotetramerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in purine nucleobase biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of oxidative phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to type I interferon IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of BRISC complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine hydroxymethyltransferase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mustela putorius furo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1176430v1.1 Primary Assembly

Genomic

  1. NW_025422127.1 Reference ASM1176430v1.1 Primary Assembly

    Range
    2558538..2563542
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004773182.3 → XP_004773239.1  serine hydroxymethyltransferase, mitochondrial

    UniProtKB/TrEMBL
    G9KNS2, M3XRQ4
    Related
    ENSMPUP00000001754.1
    Conserved Domains (2) summary
    PLN03226
    Location:45 → 502
    PLN03226; serine hydroxymethyltransferase; Provisional
    pfam00464
    Location:49 → 448
    SHMT; Serine hydroxymethyltransferase
Nucleotide Protein
Heading Accession and Version

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