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TLR4 toll like receptor 4 [ Echinops telfairi (small Madagascar hedgehog) ]

Gene ID: 101660600, updated on 20-Sep-2024

Summary

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Gene symbol
TLR4
Gene description
toll like receptor 4
Gene type
protein coding
RefSeq status
MODEL
Organism
Echinops telfairi
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Tenrecidae; Tenrecinae; Echinops
Orthologs
human mouse all
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Genomic context

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See TLR4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
103 current ASM31398v2 (GCF_000313985.2) Unplaced Scaffold NW_022111310.1 (21604523..21616252)
101 previous assembly EchTel2.0 (GCF_000313985.1) Unplaced Scaffold NW_004558766.1 (5096883..5107174)

NW_022111310.1Genomic Context describing neighboring genes Neighboring gene astrotactin 2 Neighboring gene phosphoglycerate mutase 1-like Neighboring gene galectin-3-like Neighboring gene transient receptor potential cation channel subfamily M member 4-like Neighboring gene U1 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables lipopolysaccharide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipopolysaccharide immune receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response to Gram-negative bacterium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
toll-like receptor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Echinops telfairi Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM31398v2 Primary Assembly

Genomic

  1. NW_022111310.1 Reference ASM31398v2 Primary Assembly

    Range
    21604523..21616252
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004712585.2 → XP_004712642.1  toll-like receptor 4

    Conserved Domains (6) summary
    TIGR00864
    Location:550 → 621
    PCC; polycystin cation channel protein
    sd00031
    Location:333 → 354
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:401 → 423
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:57 → 114
    LRR_8; Leucine rich repeat
    pfam01582
    Location:677 → 817
    TIR; TIR domain
    NF033189
    Location:91 → 386
    internalin_A; class 1 internalin InlA
Nucleotide Protein
Heading Accession and Version

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