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MCC MCC regulator of WNT signaling pathway [ Echinops telfairi (small Madagascar hedgehog) ]

Gene ID: 101660245, updated on 20-Sep-2024

Summary

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Gene symbol
MCC
Gene description
MCC regulator of WNT signaling pathway
Gene type
protein coding
RefSeq status
MODEL
Organism
Echinops telfairi
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Tenrecidae; Tenrecinae; Echinops
Orthologs
human mouse all
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Genomic context

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See MCC in Genome Data Viewer
Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
103 current ASM31398v2 (GCF_000313985.2) Unplaced Scaffold NW_022111373.1 (30876343..31208485)
101 previous assembly EchTel2.0 (GCF_000313985.1) Unplaced Scaffold NW_004558725.1 (20338272..20666456)

NW_022111373.1Genomic Context describing neighboring genes Neighboring gene cold shock domain-containing protein E1-like Neighboring gene 60S ribosomal protein L36a-like Neighboring gene ubiquitin-conjugating enzyme E2 C-like Neighboring gene U6 snRNA-associated Sm-like protein LSm3 Neighboring gene decapping mRNA 2 Neighboring gene 40S ribosomal protein S3a-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
colorectal mutant cancer protein
Names
MCC, WNT signaling pathway regulator
mutated in colorectal cancers

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Echinops telfairi Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM31398v2 Primary Assembly

Genomic

  1. NW_022111373.1 Reference ASM31398v2 Primary Assembly

    Range
    30876343..31208485
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013005658.2 → XP_012861112.1  colorectal mutant cancer protein

    Conserved Domains (3) summary
    COG1196
    Location:532 → 795
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:23 → 263
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam10506
    Location:376 → 439
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
Nucleotide Protein
Heading Accession and Version

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