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CISH cytokine inducible SH2 containing protein [ Ochotona princeps (American pika) ]

Gene ID: 101535444, updated on 8-Mar-2024

Summary

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Gene symbol
CISH
Gene description
cytokine inducible SH2 containing protein
Gene type
protein coding
RefSeq status
MODEL
Organism
Ochotona princeps
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Ochotonidae; Ochotona
Orthologs
human mouse all
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Genomic context

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See CISH in Genome Data Viewer
Location:
chromosome: 21
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_07 current mOchPri1.hap1 (GCF_030435755.1) 21 NC_080852.1 (25724190..25729641)
102 previous assembly OchPri4.0 (GCF_014633375.1) 9A NC_050565.1 (18638490..18642662, complement)

Chromosome 21 - NC_080852.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC131482906 Neighboring gene MAPK activated protein kinase 3 Neighboring gene HemK methyltransferase family member 1 Neighboring gene chromosome 21 C3orf18 homolog Neighboring gene calcium voltage-gated channel auxiliary subunit alpha2delta 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytokine-inducible SH2-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030435755.1-RS_2023_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOchPri1.hap1

Genomic

  1. NC_080852.1 Reference mOchPri1.hap1

    Range
    25724190..25729641
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004581505.2 → XP_004581562.1  cytokine-inducible SH2-containing protein

    Conserved Domains (2) summary
    cd10718
    Location:77 → 164
    SH2_CIS; Src homology 2 (SH2) domain found in cytokine-inducible SH2-containing protein (CIS)
    cd03734
    Location:216 → 256
    SOCS_CIS1; SOCS (suppressors of cytokine signaling) box of CIS (cytokine-inducible SH2 protein) 1-like proteins. Together with the SOCS proteins, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. ...
Nucleotide Protein
Heading Accession and Version

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