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DGKA diacylglycerol kinase alpha [ Ochotona princeps (American pika) ]

Gene ID: 101534969, updated on 18-Sep-2024

Summary

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Gene symbol
DGKA
Gene description
diacylglycerol kinase alpha
Gene type
protein coding
RefSeq status
MODEL
Organism
Ochotona princeps
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Ochotonidae; Ochotona
Orthologs
human mouse all
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Genomic context

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See DGKA in Genome Data Viewer
Location:
chromosome: 15
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2023_07 current mOchPri1.hap1 (GCF_030435755.1) 15 NC_080846.1 (16105085..16128367)
102 previous assembly OchPri4.0 (GCF_014633375.1) 4 NC_050539.1 (17337586..17364169)

Chromosome 15 - NC_080846.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 198-like Neighboring gene matrix metallopeptidase 19 Neighboring gene PYM homolog 1, exon junction complex associated factor Neighboring gene premelanosome protein Neighboring gene cyclin dependent kinase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030435755.1-RS_2023_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOchPri1.hap1

Genomic

  1. NC_080846.1 Reference mOchPri1.hap1

    Range
    16105085..16128367
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_058673829.1 → XP_058529812.1  diacylglycerol kinase alpha isoform X2

  2. XM_058673828.1 → XP_058529811.1  diacylglycerol kinase alpha isoform X2

  3. XM_058673830.1 → XP_058529813.1  diacylglycerol kinase alpha isoform X2

  4. XM_058673827.1 → XP_058529810.1  diacylglycerol kinase alpha isoform X1

  5. XM_036492345.2 → XP_036348238.1  diacylglycerol kinase alpha isoform X3

    Conserved Domains (6) summary
    smart00045
    Location:557 → 738
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:415 → 536
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:151 → 220
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:42 → 147
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20890
    Location:307 → 368
    C1_DGKalpha_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase alpha (DAG kinase alpha) and similar proteins
    cl00040
    Location:238 → 298
    C1; protein kinase C conserved region 1 (C1 domain) superfamily
Nucleotide Protein
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